{"id":"W3021290569","doi":"10.1111/dom.14079","title":"The effect of glucagon‐like peptide‐1 receptor agonists liraglutide and semaglutide on cardiovascular and renal outcomes across baseline blood pressure categories: Analysis of the <scp>LEADER</scp> and <scp>SUSTAIN</scp> 6 trials","year":2020,"lang":"en","type":"article","venue":"Diabetes Obesity and Metabolism","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Sun Pharma; Novo Nordisk; Valeant Pharmaceuticals International; American Heart Association; Sanofi; HLS Therapeutics; Amgen; AstraZeneca; Eli Lilly and Company","keywords":"Semaglutide; Liraglutide; Mace; Medicine; Diabetic nephropathy; Internal medicine; Nephropathy; Blood pressure; Type 2 diabetes; Diabetes mellitus; Dulaglutide; Endocrinology; Placebo; Cardiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01274631,0.00106669,0.0059145,0.0005231258,0.0002784798,0.00148046,0.0007077165,0.001131905,0.001498766],"category_scores_gemma":[0.01306574,0.0004474767,0.008406683,0.001065509,0.0006335636,0.00113575,0.0005458193,0.001701842,0.0001762089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006313373,"about_ca_system_score_gemma":0.0009457758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006714612,"about_ca_topic_score_gemma":0.001426939,"domain_scores_codex":[0.9893575,0.007721243,0.001154749,0.0007642657,0.0006191916,0.000383062],"domain_scores_gemma":[0.9913492,0.005510482,0.001704689,0.000621116,0.0004760849,0.0003382654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.7955362,0.0004589287,0.01746885,0.008585839,0.1299653,0.0001885043,0.0001703918,0.001320177,0.002687503,0.000327536,0.00147166,0.04181897],"study_design_scores_gemma":[0.4392225,0.09699012,0.1401183,0.002015449,0.3049611,0.0006846858,0.0003756466,0.003926512,0.002184828,0.002590285,0.006756192,0.0001743236],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8745671,0.1173343,0.001429524,0.001165336,0.0003162876,0.001010027,0.001836621,0.00005632591,0.002284421],"genre_scores_gemma":[0.9854455,0.009542723,0.001040551,0.0008496617,0.0002808992,0.0008094719,0.001369715,0.00002388069,0.0006376071],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01274631,"threshold_uncertainty_score":0.06740969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01196785227385844,"score_gpt":0.245136943228653,"score_spread":0.2331690909547946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}