{"id":"W3021311268","doi":"10.1039/d0ra03235b","title":"One-pot oxime ligation from peptides bearing thiazolidine and aminooxyacetyl groups","year":2020,"lang":"en","type":"article","venue":"RSC Advances","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nautical Research Society","funders":"Université de Paris; Centre National de la Recherche Scientifique; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche","keywords":"Thiazolidine; Oxime; Bearing (navigation); Chemistry; Ligation; Combinatorial chemistry; Medicinal chemistry; Stereochemistry; Internal medicine; Medicine; Computer science; Artificial intelligence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004080136,0.0006669362,0.0004224585,0.000168205,0.000253337,0.0002455794,0.0004773408,0.0004419505,0.001684899],"category_scores_gemma":[0.0002901672,0.0002722846,0.0002740779,0.0002160658,0.0002891818,0.0004109939,0.0007151646,0.0009392806,0.0007841431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002017757,"about_ca_system_score_gemma":0.000228184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002049748,"about_ca_topic_score_gemma":0.0003931843,"domain_scores_codex":[0.9998092,0.00003328588,0.00001762403,0.00004337374,0.00003533902,0.00006114216],"domain_scores_gemma":[0.9998637,0.000030331,0.00003713585,0.00002610136,0.00001355582,0.00002903482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001119145,0.00004170505,0.00009213899,0.0002397922,0.00001407485,0.0003261376,0.0001211781,0.0002383072,0.9913055,0.0006501071,0.0002821024,0.006577011],"study_design_scores_gemma":[0.0000188738,0.0002022528,0.0002613809,0.000006143081,0.000009661539,0.0003335483,0.00001698043,0.0003997296,0.9949726,0.00008439938,0.003681447,0.00001309712],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8921102,0.003250355,0.09292061,0.0005474121,0.0001858223,0.0003273181,0.0007543165,0.0008303442,0.009073708],"genre_scores_gemma":[0.9641915,0.00179317,0.02616994,0.00010152,0.00002685951,0.0001757264,0.0004700687,0.00007015725,0.007001051],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001684899,"threshold_uncertainty_score":0.005636573,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01330018224441458,"score_gpt":0.2293199884619948,"score_spread":0.2160198062175802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}