{"id":"W3021548203","doi":"10.1128/aac.00145-20","title":"<i>In Vitro</i> and <i>In Vivo</i> Antibiotic Capacity of Two Host Defense Peptides","year":2020,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; CYTED Ciencia y Tecnología para el Desarrollo; Consejo Nacional de Ciencia y Tecnología; Government of Canada","keywords":"Microbiology; Staphylococcus aureus; Salmonella enterica; In vitro; Antimicrobial; Pseudomonas aeruginosa; In vivo; Salmonella; Bacteria; Antibiotics; Host (biology); Serotype; Antimicrobial peptides; Pathogenic bacteria; Biology; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003223683,0.00046767,0.0002053403,0.0001671533,0.00007961423,0.0001370729,0.0001405092,0.0002511609,0.001112581],"category_scores_gemma":[0.0002539365,0.000117638,0.0002220659,0.0001091818,0.0002115396,0.0001986674,0.00009357344,0.0003919357,0.0001925067],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009386164,"about_ca_system_score_gemma":0.0001246127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002255541,"about_ca_topic_score_gemma":0.0002013155,"domain_scores_codex":[0.9998147,0.00008181341,0.00001225902,0.00002407371,0.00002226261,0.00004484651],"domain_scores_gemma":[0.9997421,0.000100276,0.00005562714,0.00002589425,0.00003201663,0.00004400075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001099396,0.0001602436,0.0001341939,0.00007521721,0.000009696995,0.00002761761,0.00001216826,0.0001900256,0.9963741,0.00003878069,0.00004864638,0.001829907],"study_design_scores_gemma":[0.00005870324,0.007048348,0.001849574,0.000006139806,0.00002296111,0.0001298042,0.00001255334,0.0002614305,0.9899701,0.00001669716,0.0006195986,0.000004109914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952465,0.001803309,0.001203661,0.00006326086,0.00003445986,0.00003396783,0.0002680014,0.00002777015,0.001319173],"genre_scores_gemma":[0.9957603,0.0008467028,0.001692691,0.00006973145,0.00003128088,0.00003712727,0.0006674862,0.00001043191,0.000884219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001112581,"threshold_uncertainty_score":0.003721952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01496000912222325,"score_gpt":0.2275661041401152,"score_spread":0.2126060950178919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}