{"id":"W3021629136","doi":"10.1016/j.fertnstert.2020.03.006","title":"Failing to mature: somatic cell dysfunction in the spermatogenic niche among patients with Sertoli cell–only and Klinefelter syndromes","year":2020,"lang":"en","type":"letter","venue":"Fertility and Sterility","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Seminiferous tubule; Sertoli cell; Biology; Germ cell; Spermatogenesis; Somatic cell; Endocrinology; Internal medicine; Context (archaeology); Klinefelter syndrome; Andrology; Cell biology; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007726619,0.0004923595,0.0008283723,0.0006042761,0.001329943,0.0008403487,0.0007807703,0.01108734,0.001444039],"category_scores_gemma":[0.00585883,0.000312786,0.0005397831,0.0005676129,0.001532194,0.001150336,0.0004707059,0.004730111,0.0005698465],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001222692,"about_ca_system_score_gemma":0.001024114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004498243,"about_ca_topic_score_gemma":0.005002249,"domain_scores_codex":[0.9994397,0.0001730424,0.00008087225,0.00009347472,0.0001071059,0.0001058125],"domain_scores_gemma":[0.9983676,0.0008936804,0.0001356068,0.00005468948,0.0001601854,0.0003882586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"observational","study_design_scores_codex":[0.0005444947,0.00010494,0.06843764,0.000148526,0.0000757009,0.7838852,0.0008524672,0.000451256,0.002092432,0.004869783,0.121908,0.01662961],"study_design_scores_gemma":[0.0002640609,0.0003399125,0.04866213,0.0003035608,0.0001155815,0.8786259,0.001412205,0.002486289,0.0008081488,0.01237232,0.05450623,0.0001036413],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.1916222,0.01042277,0.0009811199,0.7612732,0.01126072,0.00007064144,0.0003848689,0.0001164546,0.02386805],"genre_scores_gemma":[0.7081413,0.004720354,0.001103507,0.2340411,0.04372151,0.00005433511,0.0001834681,0.00005889381,0.007975613],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01108734,"threshold_uncertainty_score":0.008944094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01312811552813307,"score_gpt":0.2072234912796468,"score_spread":0.1940953757515138,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}