{"id":"W3021701766","doi":"10.1016/j.tiv.2020.104861","title":"Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity. How to evaluate the risk of the S-EDCs?","year":2020,"lang":"en","type":"article","venue":"Toxicology in Vitro","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Endocrine system; Hormone; Endogeny; Chemistry; Receptor; Bioassay; Biological activity; Pharmacology; Endocrinology; Internal medicine; Biology; In vitro; Biochemistry; Medicine; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002509115,0.00062501,0.001248273,0.0007969096,0.0003491607,0.001663313,0.0008105959,0.002128048,0.001899241],"category_scores_gemma":[0.003691818,0.0002803694,0.0006781588,0.0006251984,0.001422123,0.001441023,0.000521035,0.0009701753,0.001083175],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007915968,"about_ca_system_score_gemma":0.001659134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006663942,"about_ca_topic_score_gemma":0.00646386,"domain_scores_codex":[0.9979608,0.0006134017,0.0001582344,0.0002857854,0.0008977159,0.00008401107],"domain_scores_gemma":[0.9967302,0.001157504,0.0006470503,0.0001875385,0.001100936,0.0001767146],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001118221,0.0005180571,0.06646974,0.007330483,0.0006525878,0.0009467302,0.0003408905,0.004147848,0.5705258,0.006440848,0.01179882,0.3297099],"study_design_scores_gemma":[0.00007499448,0.005977463,0.087244,0.001650742,0.001052669,0.004750835,0.002276568,0.003110472,0.6880832,0.01237136,0.1932094,0.0001982796],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.287821,0.554077,0.09190426,0.0296246,0.002597294,0.000536249,0.004312132,0.0005148646,0.02861259],"genre_scores_gemma":[0.6026185,0.3380129,0.03899517,0.006989362,0.00105936,0.0003339678,0.001931512,0.0001300188,0.009929217],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.006663942,"threshold_uncertainty_score":0.01326966,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02036950227788226,"score_gpt":0.3288765466598726,"score_spread":0.3085070443819904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}