{"id":"W3021760220","doi":"10.1089/brain.2020.0937","title":"Hypermetabolic Cerebellar Connectome in Alzheimer's Disease","year":2021,"lang":"en","type":"article","venue":"Brain Connectivity","topic":"Functional Brain Connectivity Studies","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Winnipeg; University of Manitoba; Health Sciences Centre","funders":"Johnson and Johnson Pharmaceutical Research and Development; Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Mitacs; Eisai; Janssen Alzheimer Immunotherapy Research And Development; Northern California Institute for Research and Education; Pfizer; Novartis Pharmaceuticals Corporation; University of Southern California; Biogen; Eli Lilly and Company; Bristol-Myers Squibb; Natural Sciences and Engineering Research Council of Canada; BioClinica; U.S. Department of Defense; Meso Scale Diagnostics; National Institute on Aging; Alzheimer's Association","keywords":"Connectome; Neuroscience; Functional connectivity; Cerebellum; Alzheimer's disease; Resting state fMRI; Psychology; Disease; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004818869,0.0002657165,0.0002167506,0.0009862216,0.0003132241,0.000440979,0.0002100491,0.0003341782,0.001940981],"category_scores_gemma":[0.001151097,0.0001149601,0.0001263592,0.0008967295,0.0003805304,0.0004024123,0.0003430766,0.0002162657,0.0001254461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003529475,"about_ca_system_score_gemma":0.00025348,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002872408,"about_ca_topic_score_gemma":0.006798774,"domain_scores_codex":[0.9999158,0.00002503155,0.000007309176,0.00002783431,0.00001436076,0.00000967676],"domain_scores_gemma":[0.9995579,0.0001364224,0.000201304,0.00002774645,0.00003934234,0.00003731613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002852216,0.0002082381,0.6532512,0.001581464,0.001007673,0.00419733,0.001755804,0.006668593,0.1458564,0.00703059,0.003141413,0.1724491],"study_design_scores_gemma":[0.0000241914,0.0001063802,0.9888915,0.00005097342,0.0001021649,0.002025776,0.0001290448,0.001663539,0.002383393,0.003629415,0.000982309,0.00001123016],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925379,0.0033298,0.001590959,0.0003108238,0.00001226761,0.00001289803,0.0004279687,0.00002637073,0.00175101],"genre_scores_gemma":[0.9976222,0.0009165688,0.0008697294,0.00003351122,0.00002028765,0.00001404587,0.0002465157,0.000004394898,0.0002726641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002872408,"threshold_uncertainty_score":0.00649327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04834661996786381,"score_gpt":0.2829456714555824,"score_spread":0.2345990514877186,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}