{"id":"W3021897149","doi":"10.1158/2326-6074.tumimm18-b63","title":"Abstract B63: Immune gene expression profiling of acute myeloid leukemia identifies predictors of survival and actionable targets for treatment","year":2020,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Immune system; Myeloid; Immunotherapy; Immune checkpoint; Cancer immunotherapy; Biology; Gene expression profiling; Tumor microenvironment; Immunology; Cancer research; Innate immune system; Medicine; Gene; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008041782,0.0002208501,0.0007956854,0.0003151642,0.0002142858,0.00001638661,0.0002914191,0.0002835164,0.0002143224],"category_scores_gemma":[0.0004029078,0.0001812199,0.0001551986,0.0004277089,0.0008567217,0.0001638597,0.0003019066,0.0004972454,0.000008109909],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009172309,"about_ca_system_score_gemma":0.001971101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005518284,"about_ca_topic_score_gemma":0.000008117403,"domain_scores_codex":[0.9974419,0.0001650171,0.0005868076,0.0005418283,0.0005783536,0.0006860665],"domain_scores_gemma":[0.9977562,0.0005159804,0.0001838001,0.0004437193,0.0009172824,0.0001830502],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005631721,0.00009760195,0.009233135,0.0005917752,0.001272546,0.0000241292,0.0008775352,0.0000193644,0.9790938,0.00003907971,0.0008816915,0.002237588],"study_design_scores_gemma":[0.004170787,0.001447062,0.02858848,0.0001402772,0.0001112972,0.00001273199,0.001109222,0.0001823458,0.9627033,0.00005102734,0.001370324,0.0001131728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841586,0.01173877,0.0001005774,0.001439943,0.0002361218,0.001657075,0.0003335539,0.00003873232,0.0002965632],"genre_scores_gemma":[0.9836991,0.01257227,0.001212363,0.0000138646,0.0002775236,0.0006516725,0.0002260808,0.00005859284,0.001288502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01935535,"threshold_uncertainty_score":0.7389933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06833407773161575,"score_gpt":0.3758171426905015,"score_spread":0.3074830649588858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}