{"id":"W3022053231","doi":"10.1016/j.jconrel.2020.05.001","title":"Importance of the fatty acid chain length on in vitro and in vivo anticancer activity of fattigation-platform albumin nanoparticles in human colorectal cancer xenograft mice model","year":2020,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Ministry of Science and ICT, South Korea; National Research Foundation of Korea; Ministry of Science, ICT and Future Planning","keywords":"In vivo; Chemistry; Conjugated system; Fatty acid; Albumin; Doxorubicin; In vitro; Serum albumin; Biochemistry; Biophysics; Organic chemistry; Biology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003309574,0.000130221,0.0005342712,0.00007761233,0.00002260796,0.000006168417,0.0001404334,0.00008557407,0.000003992811],"category_scores_gemma":[0.0001948419,0.00009533363,0.0001344339,0.0001599307,0.00010578,0.00001700629,0.00003435754,0.0002183265,2.895101e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003759284,"about_ca_system_score_gemma":0.0002466318,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001094665,"about_ca_topic_score_gemma":0.001209363,"domain_scores_codex":[0.9988257,0.00008759344,0.0005693113,0.0001594055,0.0001890688,0.0001689387],"domain_scores_gemma":[0.9991714,0.00003536571,0.000526902,0.0001025823,0.00008544891,0.00007830252],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00905244,0.0001523479,0.01095076,0.00003347889,0.0000441715,8.155683e-7,0.0003038215,0.00406981,0.9745052,0.00001871885,0.00007798072,0.0007904534],"study_design_scores_gemma":[0.01068163,0.0001873819,0.02472457,0.00007607296,0.0000352882,0.000002370968,0.00008857251,0.006803701,0.9571794,0.00004337986,0.00008155406,0.0000960784],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968836,0.001813296,0.00003530856,0.0006962854,0.0002031684,0.0003068306,0.00003082202,9.326829e-7,0.00002972548],"genre_scores_gemma":[0.9986753,0.0006308517,0.00005852634,0.0002328319,0.0003653543,0.00001772211,7.149592e-7,0.00001036396,0.000008320439],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01732579,"threshold_uncertainty_score":0.3887593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01068490881960569,"score_gpt":0.2523891534390297,"score_spread":0.2417042446194241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}