{"id":"W3022171106","doi":"10.1016/j.molmet.2020.101008","title":"The gut hormone receptor GIPR links energy availability to the control of hematopoiesis","year":2020,"lang":"en","type":"article","venue":"Molecular Metabolism","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"CIHR Skin Research Training Centre; Banting and Best Diabetes Centre, University of Toronto; Azrieli Foundation; Canadian Institutes of Health Research; Novo Nordisk; International Development Research Centre; Canada-Israel Industrial Research and Development Foundation; Diabetes Canada; Novo Nordisk Fonden; Israel Science Foundation; Ontario Research Foundation; Canadian Foundation for AIDS Research; Canadian Diabetes Association","keywords":"Haematopoiesis; Biology; Hormone; Endocrinology; Receptor; Internal medicine; Genetics; Medicine; Stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009376101,0.000410817,0.0002287055,0.0002628957,0.000132968,0.0003375375,0.0001766018,0.0002675093,0.0009999698],"category_scores_gemma":[0.00009739799,0.0001830972,0.0001882031,0.0001340409,0.0003625657,0.000217814,0.0003086263,0.0009412174,0.0002626307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002019278,"about_ca_system_score_gemma":0.0001387954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003251778,"about_ca_topic_score_gemma":0.0004476311,"domain_scores_codex":[0.9998729,0.00002148266,0.000008976835,0.00003640031,0.00002954457,0.00003067921],"domain_scores_gemma":[0.9999131,0.000007378997,0.00003740901,0.000007837086,0.000006960358,0.0000273531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001802182,0.000009148002,0.0002469072,0.00003352688,0.000003065591,0.00005066243,0.00000680021,0.00003742602,0.9977658,0.00009066807,0.00003237353,0.001543405],"study_design_scores_gemma":[0.00006677958,0.0006893655,0.04639122,0.00002948014,0.00006169719,0.0006887886,0.0001020978,0.001285034,0.9449927,0.0002513447,0.00542551,0.00001592289],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874291,0.005598134,0.004095561,0.0002238899,0.00004471179,0.00002438745,0.0004286942,0.0001637771,0.001991759],"genre_scores_gemma":[0.9897001,0.004519927,0.002759209,0.0001214094,0.00003044891,0.00003316528,0.0004404431,0.00003225181,0.002363046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009999698,"threshold_uncertainty_score":0.003345191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0104917580551406,"score_gpt":0.2305091921997246,"score_spread":0.220017434144584,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}