{"id":"W3022223690","doi":"10.3389/fmed.2020.00162","title":"Intravenous Cyclophosphamide in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. An Open-Label Phase II Study","year":2020,"lang":"en","type":"article","venue":"Frontiers in Medicine","topic":"Fibromyalgia and Chronic Fatigue Syndrome Research","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Haukeland Universitetssjukehus; Helse- og Omsorgsdepartementet; Kavlifondet","keywords":"Medicine; Chronic fatigue syndrome; Cyclophosphamide; Internal medicine; Etiology; Encephalomyelitis; Chemotherapy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001270627,0.0005288927,0.001862444,0.0006099827,0.0001800951,0.00004117963,0.001160766,0.0002439266,0.001056516],"category_scores_gemma":[0.0005496738,0.0004650656,0.00004548287,0.001697947,0.0005136316,0.000425069,0.0004464264,0.001389275,0.00003234897],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001003207,"about_ca_system_score_gemma":0.001016214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001267406,"about_ca_topic_score_gemma":0.00007054253,"domain_scores_codex":[0.9948229,0.0003842977,0.001208825,0.001233839,0.001166853,0.001183274],"domain_scores_gemma":[0.9978082,0.00007523861,0.0001663226,0.0008937361,0.0001134057,0.0009430791],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.01375338,0.05767894,0.243732,0.01327035,0.001793314,0.1012869,0.1173529,0.000362761,0.02215227,0.000556307,0.09377018,0.3342907],"study_design_scores_gemma":[0.3077932,0.3915941,0.1899128,0.01101438,0.0006320525,0.001745281,0.05201922,0.03684784,0.0004607361,0.001565024,0.003976259,0.002439008],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9776646,0.007868562,0.001432641,0.00711628,0.0007098672,0.004030033,0.00001549446,0.000114102,0.001048388],"genre_scores_gemma":[0.9944522,0.0007165116,0.003399256,0.0002541254,0.0001796609,0.0002637265,0.0001757198,0.00009708155,0.0004617037],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3339152,"threshold_uncertainty_score":0.9998567,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06184406887044093,"score_gpt":0.3636189585158185,"score_spread":0.3017748896453776,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}