{"id":"W3022544901","doi":"10.1101/2020.05.07.082370","title":"MEIS-WNT5A axis regulates development of 4 <sup>th</sup> ventricle choroid plexus","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Intégré Universitaire de Santé et de Services Sociaux du Saguenay–Lac-Saint-Jean; Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Neuron Nadační Fond Na Podporu Vědy; Masarykova Univerzita; European Social Fund; Central European Institute of Technology; KWF Kankerbestrijding; Hjärnfonden; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Vetenskapsrådet; Grantová Agentura České Republiky; Universiteit van Amsterdam; Cancerfonden; Ministerstvo Školství, Mládeže a Tělovýchovy; Stiftelsen för Strategisk Forskning; Karolinska Institutet; European Regional Development Fund; European Commission","keywords":"Choroid plexus; Wnt signaling pathway; Ventricle; WNT5A; Cerebrospinal fluid; Cell biology; Fourth ventricle; Morphogenesis; Epithelium; Anatomy; Biology; Chemistry; Internal medicine; Endocrinology; Signal transduction; Neuroscience; Medicine; Gene; Central nervous system; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001244845,0.0004157519,0.0002279505,0.0005780322,0.0002995118,0.0005612163,0.0002058368,0.0003316025,0.002127396],"category_scores_gemma":[0.0001088551,0.0003059965,0.0002484813,0.0001308552,0.0004460874,0.000258156,0.0004344216,0.000716933,0.00076725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008466662,"about_ca_system_score_gemma":0.0004602087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002609857,"about_ca_topic_score_gemma":0.003503572,"domain_scores_codex":[0.9997858,0.00002198004,0.00001645547,0.00006163285,0.0000604275,0.00005369052],"domain_scores_gemma":[0.9998167,0.00001070365,0.00007138494,0.000008870898,0.00002112702,0.0000712604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006186178,0.000003824573,0.0004131961,0.00002119045,0.000002642071,0.00007131752,0.00001228937,0.00003158678,0.9986202,0.0002078359,0.00005876835,0.0004953055],"study_design_scores_gemma":[0.00001182634,0.0000438188,0.02521856,0.00001378457,0.000009395876,0.0002467819,0.00006966436,0.0009919686,0.9694843,0.00008432395,0.003819739,0.000005989494],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9801648,0.003922291,0.007223147,0.0002223146,0.00006011578,0.00004472085,0.001896455,0.0003994023,0.006066759],"genre_scores_gemma":[0.9849653,0.0008464129,0.002413815,0.00007961025,0.00000981368,0.00004119909,0.001001733,0.00009171958,0.01055026],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002609857,"threshold_uncertainty_score":0.007116914,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01162377733495564,"score_gpt":0.2124173175189232,"score_spread":0.2007935401839676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}