{"id":"W3022593880","doi":"10.1038/s41564-020-0721-1","title":"Moving from probiotics to precision probiotics","year":2020,"lang":"en","type":"letter","venue":"Nature Microbiology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":224,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Institute for Advanced Research","funders":"Howard Hughes Medical Institute","keywords":"Probiotic; Precision medicine; Computational biology; Microbiome; Biology; Bioinformatics; Genetics; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0001403542,0.000852304,0.000929739,0.0001841845,0.0001789393,0.00007550451,0.001173157,0.007286802,0.0001028577],"category_scores_gemma":[0.0002703796,0.000796742,0.0003346356,0.0002584445,0.0001499132,0.000003684464,0.0008715288,0.004996771,0.00048821],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001203131,"about_ca_system_score_gemma":0.0004739386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002289229,"about_ca_topic_score_gemma":0.00009470358,"domain_scores_codex":[0.9959834,0.0002988204,0.0006855491,0.001867711,0.0001177225,0.001046757],"domain_scores_gemma":[0.9980022,0.00007520889,0.0003418779,0.001102221,0.0002672395,0.0002111932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009749337,0.00002016288,0.00002186522,0.00008379039,0.00009242565,0.00005612016,0.00004905679,0.000003031177,0.481849,0.000002081993,0.5175164,0.0002086239],"study_design_scores_gemma":[0.000433027,0.0008331825,0.00004342113,0.0001271671,0.00008445571,0.000101001,0.0000122786,0.000001846112,0.09504054,0.00005106683,0.9024932,0.0007787992],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.03744347,0.006488527,0.00078661,0.9388043,0.005912881,0.003306891,0.006400696,0.000203823,0.0006528466],"genre_scores_gemma":[0.009011474,0.0002222337,0.01193846,0.9387553,0.01042453,0.00002473739,0.02674781,0.0002285547,0.00264685],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.3868084,"threshold_uncertainty_score":0.9994484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007031432463853401,"score_gpt":0.2485453123003697,"score_spread":0.2415138798365163,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}