{"id":"W3022593880","doi":"10.1038/s41564-020-0721-1","title":"Moving from probiotics to precision probiotics","year":2020,"lang":"en","type":"letter","venue":"Nature Microbiology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":224,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Institute for Advanced Research","funders":"Howard Hughes Medical Institute","keywords":"Probiotic; Precision medicine; Computational biology; Microbiome; Biology; Bioinformatics; Genetics; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004716596,0.000762392,0.001333453,0.0005904188,0.002154474,0.0035815,0.0012987,0.02627715,0.006405572],"category_scores_gemma":[0.01952496,0.0005137175,0.0007253921,0.0004195193,0.004406305,0.004340605,0.001900788,0.03093553,0.005121671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002913747,"about_ca_system_score_gemma":0.002145503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001872445,"about_ca_topic_score_gemma":0.003558011,"domain_scores_codex":[0.9974875,0.0007574865,0.0002181341,0.0003372912,0.0009298966,0.0002697375],"domain_scores_gemma":[0.9896333,0.006848683,0.0004043832,0.00038799,0.001410153,0.001315481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001604717,0.00004854826,0.0002450785,0.00008104826,0.00001820178,0.0005031789,0.00006066953,0.00005960295,0.0004058029,0.006697673,0.97134,0.02037959],"study_design_scores_gemma":[0.0002263693,0.00010559,0.0006249529,0.0001847084,0.00002529505,0.0006160374,0.0002530947,0.0004153079,0.0005084493,0.03365731,0.9633375,0.00004542015],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0002811461,0.005080355,0.0002499705,0.9487168,0.04369195,0.000007267784,0.00003646623,0.00003888338,0.001897178],"genre_scores_gemma":[0.005073976,0.003514098,0.0004152512,0.9062896,0.07853051,0.00003392549,0.00002077726,0.00003050892,0.006091405],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02627715,"threshold_uncertainty_score":0.02494401,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007031432463853401,"score_gpt":0.2485453123003697,"score_spread":0.2415138798365163,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}