{"id":"W3022674989","doi":"10.3389/fcimb.2020.00210","title":"Precision Health for Chagas Disease: Integrating Parasite and Host Factors to Predict Outcome of Infection and Response to Therapy","year":2020,"lang":"en","type":"review","venue":"Frontiers in Cellular and Infection Microbiology","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; National Institute of General Medical Sciences; International Union of Biochemistry and Molecular Biology","keywords":"Chagas disease; Disease; Trypanosoma cruzi; Immunology; Megaesophagus; Megacolon; Parasite hosting; Zoonosis; Virulence; Medicine; Epidemiology; Biology; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001581944,0.0007450461,0.001678387,0.001839924,0.0002348369,0.001179251,0.001085399,0.001716481,0.003162974],"category_scores_gemma":[0.00291732,0.0002514523,0.0008323074,0.001308046,0.0005812803,0.001422279,0.0007744151,0.002739699,0.001948251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009709112,"about_ca_system_score_gemma":0.001541571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001086857,"about_ca_topic_score_gemma":0.00189123,"domain_scores_codex":[0.9995511,0.0001418869,0.00007345695,0.00006295869,0.0001362357,0.00003441699],"domain_scores_gemma":[0.9985818,0.0009872848,0.00009841966,0.00003125499,0.0002421053,0.00005907571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008117828,0.00006014781,0.0002046597,0.02116677,0.0002204099,0.00008540008,0.00006816431,0.0003014719,0.0005312058,0.006127325,0.03060836,0.9405449],"study_design_scores_gemma":[0.0000332184,0.0001573722,0.0009182559,0.01234263,0.0002703295,0.0005581721,0.00007903222,0.0001567405,0.0002676427,0.004686516,0.9805002,0.00002986213],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004200063,0.9984084,0.000114771,0.0006340549,0.000317992,0.00000519801,0.0000197353,0.000007527067,0.0004502728],"genre_scores_gemma":[0.0004203081,0.9985275,0.0002054574,0.0003906191,0.0002262052,0.000009076469,0.00002588989,0.00000159813,0.0001933631],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003162974,"threshold_uncertainty_score":0.0105812,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04849631958570867,"score_gpt":0.3774914877592598,"score_spread":0.3289951681735512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}