{"id":"W3023014256","doi":"10.3390/cancers12051208","title":"Methylation-Based Signatures for Gastroesophageal Tumor Classification","year":2020,"lang":"en","type":"article","venue":"Cancers","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Alberta Innovates","keywords":"Methylation; DNA methylation; Cancer; Carcinogenesis; Cancer research; Biology; Computational biology; Gene; Oncology; Medicine; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005205266,0.0000941558,0.00008018529,0.00001985067,0.00005556867,0.00001278301,0.0000870864,0.00008031099,0.00002251044],"category_scores_gemma":[0.00007593151,0.0001015416,0.00007636321,0.00009106334,0.0000360164,0.000002854438,0.000008864472,0.000050315,0.000003422891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000154913,"about_ca_system_score_gemma":0.0004208208,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007679649,"about_ca_topic_score_gemma":0.00001366674,"domain_scores_codex":[0.9993613,0.00002069391,0.0001249541,0.000273757,0.00008267588,0.0001366384],"domain_scores_gemma":[0.9996044,0.00001225397,0.00008555366,0.0001333853,0.00008536995,0.00007901365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002825024,0.000003093122,0.0002085518,0.00002763794,0.00003012736,2.422123e-7,0.00002751891,0.1365758,0.846192,0.00007511069,0.01258342,0.00399401],"study_design_scores_gemma":[0.001480119,0.000452721,0.002868857,0.00001109307,0.00004969338,5.548902e-7,0.0000535224,0.2014568,0.7138301,0.00004797873,0.07951578,0.0002327848],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.600801,0.003726326,0.3873964,0.00451798,0.0008560381,0.001572093,0.0002496939,0.0001137454,0.0007667063],"genre_scores_gemma":[0.996049,0.000008393996,0.001538997,0.001137211,0.0006561984,0.00009721149,0.0004252542,0.00002184982,0.00006588535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.395248,"threshold_uncertainty_score":0.4140746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01831653308268282,"score_gpt":0.2660012366007099,"score_spread":0.2476847035180271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}