{"id":"W3023171487","doi":"10.1016/j.eururo.2020.05.005","title":"Prostate Cancer Risk by BRCA2 Genomic Regions","year":2020,"lang":"en","type":"article","venue":"European Urology","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"National Institute for Health and Care Research; Cancer Research UK; Royal Marsden NHS Foundation Trust","keywords":"Medicine; Prostate cancer; Hazard ratio; Internal medicine; Prospective cohort study; Oncology; Confidence interval; Cancer; Incidence (geometry); Population; Proportional hazards model; Cohort; Gynecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001150847,0.0001446128,0.000108602,0.00001815552,0.00009833383,0.00001522397,0.0002801252,0.00006117332,0.0001571845],"category_scores_gemma":[0.00009205667,0.0001507022,0.00006020304,0.00008591319,0.000131094,0.000002172375,0.0001819212,0.0001661654,0.0002743495],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000210773,"about_ca_system_score_gemma":0.00009055214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000152783,"about_ca_topic_score_gemma":0.00001436242,"domain_scores_codex":[0.9987378,0.0002896239,0.0001826585,0.0004779687,0.0000577087,0.0002542791],"domain_scores_gemma":[0.999413,0.00001011755,0.0001108628,0.0003006711,0.00004548303,0.0001198683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001794048,0.00003145566,0.007827958,0.000008774541,0.0001502635,0.00002039571,0.0005202259,0.001570829,0.5104709,0.00005273421,0.4694439,0.009723162],"study_design_scores_gemma":[0.0005275469,0.0002988342,0.004740776,8.072809e-7,0.00003812272,0.0000114776,0.00002265784,0.0001083175,0.008334753,0.00003546224,0.9856942,0.0001870075],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9646859,0.01033482,0.002867243,0.0123407,0.0004008305,0.0002744564,0.0003288462,0.00007296276,0.008694201],"genre_scores_gemma":[0.9830204,0.001641574,0.0003646294,0.01317878,0.0006297952,0.00002452064,0.0001432536,0.00007031873,0.0009267736],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5162504,"threshold_uncertainty_score":0.6145457,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01042550135419997,"score_gpt":0.2359871049903855,"score_spread":0.2255616036361855,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}