{"id":"W3023267507","doi":"10.3390/cosmetics7020029","title":"Controlled Release of Retinol in Cationic Co-Polymeric Nanoparticles for Topical Application","year":2020,"lang":"en","type":"article","venue":"Cosmetics","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Chicoutimi","funders":"","keywords":"Retinol; Cationic polymerization; Active ingredient; Particle size; Solvent; Chemistry; Nanoparticle; Chromatography; Chemical engineering; Materials science; Nanotechnology; Vitamin; Organic chemistry; Pharmacology; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007995374,0.00007284628,0.0001595916,0.00001440906,0.00002165212,0.000006376233,0.000122686,0.00008069837,0.000003197149],"category_scores_gemma":[0.0003393274,0.0000704603,0.00005802887,0.00008740118,0.00006281304,0.000001622629,0.00002072763,0.00004096412,0.000002785933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006453198,"about_ca_system_score_gemma":0.00008548544,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001518304,"about_ca_topic_score_gemma":0.000001172682,"domain_scores_codex":[0.9993531,0.00003238328,0.0002481629,0.0001834493,0.00006901421,0.0001138903],"domain_scores_gemma":[0.9996004,0.00003283158,0.00009325687,0.0001549068,0.00006903472,0.00004957028],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003910629,0.00005154968,0.003859084,0.00008606049,0.00001290362,3.663764e-7,0.00008883564,0.00007001201,0.9915828,0.0008403518,0.0002768305,0.002740196],"study_design_scores_gemma":[0.002235104,0.0002747504,0.0003186129,0.000006033464,0.00002141486,0.000001410397,0.00009095023,0.00180528,0.9905131,0.0002880781,0.004355082,0.00009022008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829223,0.001105492,0.0147698,0.0003847942,0.00002457378,0.0004194596,0.000006971062,0.00000732082,0.0003593383],"genre_scores_gemma":[0.9982248,0.000251596,0.0009192724,0.0002781095,0.00009283904,0.0001164511,0.00006445395,0.00001061891,0.00004183688],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01530257,"threshold_uncertainty_score":0.2873288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01409208129988422,"score_gpt":0.2729858439943501,"score_spread":0.2588937626944658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}