{"id":"W3023267507","doi":"10.3390/cosmetics7020029","title":"Controlled Release of Retinol in Cationic Co-Polymeric Nanoparticles for Topical Application","year":2020,"lang":"en","type":"article","venue":"Cosmetics","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Chicoutimi","funders":"","keywords":"Retinol; Cationic polymerization; Active ingredient; Particle size; Solvent; Chemistry; Nanoparticle; Chromatography; Chemical engineering; Materials science; Nanotechnology; Vitamin; Organic chemistry; Pharmacology; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001753129,0.0002893619,0.0002083232,0.0002158535,0.0001395763,0.0002738509,0.0001582878,0.0003242024,0.0006341433],"category_scores_gemma":[0.000164215,0.0001409621,0.0002526103,0.00011451,0.0001796836,0.0002252855,0.0001542855,0.0003248453,0.0003231862],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002613861,"about_ca_system_score_gemma":0.0001743319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004621023,"about_ca_topic_score_gemma":0.0006103442,"domain_scores_codex":[0.9998931,0.00001146058,0.000009053178,0.00003722236,0.00002878406,0.00002043869],"domain_scores_gemma":[0.9999138,0.00001780693,0.0000257723,0.00001061377,0.00001861243,0.00001346318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002664958,0.000008703848,0.00002577909,0.00002231745,0.000002100408,0.00002771255,0.000009149459,0.00008722641,0.998552,0.00003602443,0.0000156448,0.001186629],"study_design_scores_gemma":[0.000004724739,0.0001080439,0.0002115912,0.000002951883,0.000006520769,0.00004828978,0.000004911106,0.0005728509,0.9981546,0.000009745408,0.0008718757,0.000003865477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98353,0.00214021,0.01148641,0.00008777545,0.00005518055,0.00008576013,0.0001167091,0.0001760583,0.002321833],"genre_scores_gemma":[0.9878554,0.0006814004,0.007664534,0.00003687749,0.000009799567,0.00004491794,0.00007604605,0.0000584301,0.003572621],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006341433,"threshold_uncertainty_score":0.002121389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01409208129988422,"score_gpt":0.2729858439943501,"score_spread":0.2588937626944658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}