{"id":"W3023317071","doi":"10.1007/978-981-15-1412-8_15","title":"Neoadjuvant Chemotherapy and Biomarkers","year":2020,"lang":"en","type":"book-chapter","venue":"","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; Women's College Hospital; Mount Sinai Hospital","funders":"","keywords":"Medicine; Breast cancer; Oncology; Internal medicine; Chemotherapy; Estrogen receptor; Neoadjuvant therapy; Adjuvant; Immunohistochemistry; Adjuvant therapy; Cancer; Hormone receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006481897,0.0005475205,0.0005085073,0.0009751446,0.0002245895,0.001627203,0.0004932487,0.0008623358,0.01567622],"category_scores_gemma":[0.001252911,0.000322946,0.0002091952,0.0009899221,0.000848478,0.001546665,0.000716101,0.001550823,0.006637632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008014781,"about_ca_system_score_gemma":0.0005902345,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009423982,"about_ca_topic_score_gemma":0.002772442,"domain_scores_codex":[0.9997743,0.00008720259,0.00001183626,0.00002856792,0.00008671463,0.00001140326],"domain_scores_gemma":[0.9996684,0.0002513127,0.00001427083,0.00001936755,0.000031571,0.0000150667],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006094552,0.00005221495,0.0002673565,0.0006487448,0.00001673994,0.0001691706,0.000119978,0.0003829686,0.002135533,0.07851627,0.2654749,0.652155],"study_design_scores_gemma":[0.000003576157,0.0000270499,0.000469526,0.0003583267,0.000006935094,0.0005582415,0.00004511911,0.0001226698,0.0005224496,0.02901402,0.9688654,0.000006751675],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"other","genre_scores_codex":[0.0009927131,0.7251831,0.00865511,0.01694492,0.007072478,0.00004152933,0.0002600209,0.0001335162,0.2407166],"genre_scores_gemma":[0.01136247,0.4674888,0.009243088,0.01143507,0.005943891,0.0001240065,0.0003424344,0.0001393374,0.493921],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.01567622,"threshold_uncertainty_score":0.05244219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00932283077095267,"score_gpt":0.2192276001749081,"score_spread":0.2099047694039554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}