{"id":"W3023337720","doi":"10.1101/2020.05.04.075895","title":"PHOSPHO1, a novel skeletal regulator of insulin resistance and obesity","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; McGill University","funders":"","keywords":"Endocrinology; Internal medicine; Insulin resistance; Adipose tissue; Insulin; Biology; Osteocalcin; Diabetes mellitus; Glucose homeostasis; Regulator; Homeostasis; Chemistry; Enzyme; Medicine; Biochemistry; Gene; Alkaline phosphatase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009411725,0.0003917759,0.0002331708,0.0002589503,0.0001413264,0.0004291626,0.0002146916,0.0003573036,0.002491169],"category_scores_gemma":[0.00009937924,0.0001591148,0.0001909173,0.0001783919,0.0001765984,0.0001359549,0.0001936582,0.000379445,0.0006163624],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002205481,"about_ca_system_score_gemma":0.0001237358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001951154,"about_ca_topic_score_gemma":0.0002277699,"domain_scores_codex":[0.9999536,0.0000049557,0.000002040778,0.00001808993,0.0000119188,0.000009381307],"domain_scores_gemma":[0.9999493,0.000007753341,0.00001808174,0.000003709013,0.000003363961,0.00001771099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005880698,0.00003492952,0.002147728,0.0001561227,0.00002095106,0.0004963167,0.00001898982,0.0003204572,0.9847051,0.0006354032,0.001064314,0.009811671],"study_design_scores_gemma":[0.0002670869,0.0008564281,0.0870053,0.00008136062,0.0001394417,0.007759037,0.0001057282,0.005422144,0.8502502,0.001918134,0.04615502,0.00004009882],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9605265,0.01960626,0.00655956,0.001246887,0.0003925536,0.00004303879,0.004162176,0.0005393518,0.006923735],"genre_scores_gemma":[0.9780783,0.005211395,0.003042068,0.0003681416,0.0001441652,0.00003861667,0.003376391,0.00007018384,0.00967071],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002491169,"threshold_uncertainty_score":0.008333802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01623586255841972,"score_gpt":0.2298291461353156,"score_spread":0.2135932835768959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}