{"id":"W3023442851","doi":"10.1186/s12974-020-01811-7","title":"Embryonic microglia influence developing hypothalamic glial populations","year":2020,"lang":"en","type":"article","venue":"Journal of Neuroinflammation","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotchkiss Brain Institute; Ontario Brain Institute; Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research; Plexxikon","keywords":"Microglia; OLIG2; Gliogenesis; Biology; Progenitor cell; Neuroscience; Embryonic stem cell; Neural stem cell; Oligodendrocyte; Neuroinflammation; Neurosphere; Astrocyte; Cell biology; Immunology; Stem cell; Central nervous system; Adult stem cell; Myelin; Inflammation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000137266,0.0002704067,0.000143325,0.0002262684,0.0001678538,0.0003720163,0.0001419534,0.0001923098,0.0009809579],"category_scores_gemma":[0.0001892049,0.0001312261,0.000172489,0.00008584988,0.0002642779,0.000137007,0.0003212423,0.0004608022,0.0002213229],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003346698,"about_ca_system_score_gemma":0.000319164,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009809303,"about_ca_topic_score_gemma":0.002333107,"domain_scores_codex":[0.9998382,0.00002289072,0.00001457972,0.00002946018,0.00005030052,0.0000445763],"domain_scores_gemma":[0.9998044,0.00004376728,0.00006995958,0.00001388784,0.00003020093,0.00003787157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001706842,0.00001480588,0.0021485,0.00007922577,0.000007135618,0.0002948804,0.0001194192,0.0001366854,0.9932753,0.0003164144,0.0000694515,0.003367611],"study_design_scores_gemma":[0.00002015964,0.0002839555,0.04701348,0.00007477769,0.00005572896,0.000574259,0.0003587007,0.0008358033,0.9432382,0.0002133229,0.007320329,0.00001131423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930299,0.002623176,0.001634371,0.00008031559,0.00002813407,0.00001588064,0.0002966308,0.00004156741,0.002250005],"genre_scores_gemma":[0.9929345,0.002243776,0.001940055,0.00007643398,0.00001507225,0.00004225189,0.0002775386,0.00003855427,0.002431882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009809579,"threshold_uncertainty_score":0.003281593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09196153834959321,"score_gpt":0.2867002879315152,"score_spread":0.194738749581922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}