{"id":"W3023543087","doi":"10.1111/trf.15812","title":"Nicotine exposure increases markers of oxidant stress in stored red blood cells from healthy donor volunteers","year":2020,"lang":"en","type":"article","venue":"Transfusion","topic":"Blood transfusion and management","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Cotinine; Nicotine; Hemolysis; Oxidative stress; Snuff; Pentose phosphate pathway; Red blood cell; Chemistry; Andrology; Medicine; Hemoglobin; Physiology; Glycolysis; Biochemistry; Internal medicine; Metabolism; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001636816,0.0002324773,0.0005654723,0.0001463402,0.0000398902,0.000007092875,0.0001459467,0.0001265163,0.0007696988],"category_scores_gemma":[0.00002449423,0.0002102269,0.0001620798,0.0003373067,0.00005576109,0.00006295255,0.00002935807,0.0002767014,0.000009077132],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002772023,"about_ca_system_score_gemma":0.00007641376,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007397075,"about_ca_topic_score_gemma":0.00193065,"domain_scores_codex":[0.9981239,0.0001179837,0.0005909626,0.0004673674,0.0004140405,0.0002857705],"domain_scores_gemma":[0.9991805,0.00006322083,0.00007310345,0.0003108915,0.00005245033,0.0003198425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01260997,0.002788997,0.05706766,0.001091757,0.0002631575,0.0001555954,0.002360431,0.00009090907,0.9165119,0.00003912693,0.001204226,0.005816278],"study_design_scores_gemma":[0.0491576,0.00748122,0.1945232,0.001608746,0.001493838,0.0000102446,0.003365321,0.001660053,0.7362121,0.00002664825,0.003749972,0.0007110371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910243,0.000500367,0.0002376865,0.006325219,0.0001362557,0.001107606,0.0001213304,0.00009460041,0.0004526027],"genre_scores_gemma":[0.9953072,0.001987397,0.0009857777,0.001405159,0.00008245121,0.00002224915,0.0001079728,0.00003637276,0.00006541347],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1802998,"threshold_uncertainty_score":0.9992127,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01245210260277751,"score_gpt":0.2249039256159288,"score_spread":0.2124518230131513,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}