{"id":"W3023554288","doi":"10.3389/fcimb.2020.00197","title":"Auto Arginine-GlcNAcylation Is Crucial for Bacterial Pathogens in Regulating Host Cell Death","year":2020,"lang":"en","type":"article","venue":"Frontiers in Cellular and Infection Microbiology","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Infection and Immunity; Fundamental Research Funds for the Central Universities; Huazhong Agricultural University","keywords":"Effector; Virulence; Biology; Death domain; Type three secretion system; Salmonella enterica; Programmed cell death; Signal transduction; Cell biology; Microbiology; Secretion; Receptor; Escherichia coli; Arginine; Pathogenicity island; Biochemistry; Gene; Amino acid; Apoptosis","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008212472,0.0003114734,0.0001559916,0.00009038144,0.0001658122,0.0002315078,0.0001290298,0.0001988097,0.0006749645],"category_scores_gemma":[0.00007964559,0.00005734842,0.0002005904,0.0001132009,0.0001581985,0.0002337927,0.0002291973,0.0002910835,0.0002590456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001819399,"about_ca_system_score_gemma":0.0001558951,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003884026,"about_ca_topic_score_gemma":0.000447847,"domain_scores_codex":[0.9999094,0.00001223663,0.000006982818,0.00002131341,0.00002792568,0.00002217138],"domain_scores_gemma":[0.9999275,0.000004092381,0.0000321254,0.00000769024,0.00001212321,0.0000163187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001095658,0.00001215312,0.001624926,0.00005781179,0.000007696486,0.0001567412,0.00001818968,0.00006488026,0.9951408,0.0001122705,0.00003830277,0.002656607],"study_design_scores_gemma":[0.00001204064,0.0002164968,0.04068107,0.00001252547,0.00002537244,0.001435029,0.00007283942,0.001035861,0.9506226,0.0002886787,0.005586854,0.00001072332],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988838,0.005184731,0.004113621,0.0001280547,0.0000274974,0.0000131909,0.0002284392,0.00006969828,0.001396919],"genre_scores_gemma":[0.9945511,0.002069894,0.001350431,0.00005218741,0.00001088205,0.00000682188,0.000347968,0.000007915255,0.001602761],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006749645,"threshold_uncertainty_score":0.002258003,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01037916789135737,"score_gpt":0.2126423583856936,"score_spread":0.2022631904943362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}