{"id":"W3023631491","doi":"10.1182/bloodadvances.2020001518","title":"Patients with high-risk DLBCL benefit from dose-dense immunochemotherapy combined with early systemic CNS prophylaxis","year":2020,"lang":"en","type":"article","venue":"Blood Advances","topic":"CNS Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"Helsingin Yliopisto; Amgen","keywords":"Medicine; Internal medicine; Oncology; Intensive care medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00002451446,0.0003352735,0.0005721361,0.00004310717,0.0001128797,0.00004407717,0.0001196624,0.00006735653,0.00005390901],"category_scores_gemma":[0.00001763289,0.0002044572,0.00007786394,0.0002482968,0.00007642286,0.0001586129,0.00002500327,0.0001286017,0.00005330182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000536314,"about_ca_system_score_gemma":0.00006183357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007149891,"about_ca_topic_score_gemma":0.00007231558,"domain_scores_codex":[0.9984354,0.00002957661,0.0002786975,0.0005260218,0.0004487832,0.0002814819],"domain_scores_gemma":[0.998912,0.0000871935,0.0002360637,0.0003976066,0.0001524769,0.0002146852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004080306,0.002027499,0.9677986,0.00008324193,0.0009054352,0.0001222002,0.000688947,0.00001915372,0.0003978339,0.00002955231,0.00001768665,0.02382953],"study_design_scores_gemma":[0.03379854,0.0159129,0.9387167,0.0005199162,0.0007017734,0.0000121675,0.0001482052,0.000005427657,0.009415844,0.00004668808,0.0004125102,0.0003093115],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938173,0.004226958,0.00001528878,0.0003206158,0.00006724525,0.001149541,0.0001846009,0.0001509879,0.00006751576],"genre_scores_gemma":[0.9965637,0.000632692,0.001979578,0.0002950442,0.0001181904,0.00015522,0.0001423106,0.00006872849,0.00004448101],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02971824,"threshold_uncertainty_score":0.8337523,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004630928837424983,"score_gpt":0.1920785571373307,"score_spread":0.1874476282999057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}