{"id":"W3023782267","doi":"10.7554/elife.53999","title":"Intracellular calcium leak lowers glucose storage in human muscle, promoting hyperglycemia and diabetes","year":2020,"lang":"en","type":"article","venue":"eLife","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Toronto General Hospital; University of Toronto; University Health Network","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Center for Research Resources; National Institute of General Medical Sciences","keywords":"Diabetes mellitus; Intracellular; Calcium in biology; Calcium; Endocrinology; Internal medicine; Leak; Cell biology; Chemistry; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001583412,0.000299913,0.0002892629,0.0002421603,0.0002931883,0.0003596471,0.0002475513,0.0004684908,0.004473648],"category_scores_gemma":[0.0002452937,0.000172473,0.0002096327,0.0002373812,0.0003283526,0.0002948289,0.000361932,0.0006339348,0.0006466277],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003428057,"about_ca_system_score_gemma":0.000226862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000781286,"about_ca_topic_score_gemma":0.0010417,"domain_scores_codex":[0.9999002,0.00001048591,0.00000667929,0.00003035919,0.00002226071,0.00002999096],"domain_scores_gemma":[0.9999316,0.000008985729,0.00002179597,0.000008009913,0.00000905263,0.0000205625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002104947,0.00005763997,0.001264728,0.0001873718,0.00003068514,0.0003139291,0.00004879191,0.00007606488,0.9864975,0.000411194,0.001665379,0.007341856],"study_design_scores_gemma":[0.0006851651,0.0009360904,0.05653939,0.000121844,0.0001586193,0.00320511,0.0004589735,0.001414603,0.9037736,0.002112749,0.03054905,0.00004472744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9503488,0.0238522,0.006743829,0.005415483,0.000636161,0.00003891217,0.001395421,0.0004999269,0.01106933],"genre_scores_gemma":[0.9832372,0.006335936,0.002762561,0.0009658113,0.0001080217,0.0000477704,0.0006794987,0.00007207868,0.005791202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004473648,"threshold_uncertainty_score":0.01496589,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02287575487974982,"score_gpt":0.2646850634302756,"score_spread":0.2418093085505258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}