{"id":"W3024009988","doi":"10.1016/j.bbagen.2020.129633","title":"EcDBS1R6: A novel cationic antimicrobial peptide derived from a signal peptide sequence","year":2020,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - General Subjects","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Centre National de la Recherche Scientifique; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Sorbonne Université; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Peptide; Signal peptide; Antimicrobial peptides; Antimicrobial; Peptide sequence; Escherichia coli; Biochemistry; Biology; Membrane; Chemistry; Microbiology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002010979,0.0005330667,0.0003557858,0.0002133917,0.0001678027,0.0003705123,0.0003678884,0.0006654641,0.001212903],"category_scores_gemma":[0.000158238,0.0001102395,0.0002916783,0.0001913824,0.000281346,0.0002400226,0.0002962654,0.0006838783,0.001004342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002759221,"about_ca_system_score_gemma":0.0001872533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001632245,"about_ca_topic_score_gemma":0.0001435625,"domain_scores_codex":[0.9998983,0.00001771774,0.000009827503,0.0000270079,0.00002496886,0.00002223835],"domain_scores_gemma":[0.99991,0.00000767819,0.00001678037,0.00000487052,0.00001155433,0.00004913008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002747958,0.00002467757,0.0001472799,0.00007413874,0.000004659537,0.0003217984,0.0000103566,0.0001397769,0.9946507,0.0001221261,0.0001683573,0.00406143],"study_design_scores_gemma":[0.0001279235,0.001224488,0.002774216,0.00001836532,0.00002992492,0.004992506,0.00002599707,0.001553407,0.9665,0.0001100682,0.02261747,0.00002575056],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9734494,0.007617917,0.01306326,0.000466621,0.0004320159,0.0001326316,0.001353539,0.0003179773,0.003166634],"genre_scores_gemma":[0.9635454,0.00304123,0.02207557,0.0004465733,0.0001513405,0.00007741476,0.004079681,0.00007585114,0.006506856],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001212903,"threshold_uncertainty_score":0.004057527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02899966747406231,"score_gpt":0.2409447070925164,"score_spread":0.2119450396184541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}