{"id":"W3024072726","doi":"10.1101/2020.05.15.097576","title":"TOR signaling modulates Cdk8-dependent <i>GAL</i> gene expression in <i>Saccharomyces cerevisiae</i>","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; University of British Columbia","funders":"","keywords":"Cyclin-dependent kinase 8; Phosphorylation; Biology; Transcription (linguistics); Mutant; Gene; Saccharomyces cerevisiae; RNA polymerase II; Cell biology; Gene expression; Promoter; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005269588,0.0002892725,0.0001536255,0.0001409513,0.0001495365,0.0003493538,0.0001908335,0.0001341521,0.001352014],"category_scores_gemma":[0.000066211,0.0001195219,0.0001512619,0.0001177033,0.000162264,0.00009064979,0.0001929126,0.0003398599,0.0004648733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005299614,"about_ca_system_score_gemma":0.0001670806,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001863874,"about_ca_topic_score_gemma":0.002938346,"domain_scores_codex":[0.9999318,0.000007221119,0.000006041981,0.00001656358,0.00001556836,0.00002266021],"domain_scores_gemma":[0.9999188,0.00001128578,0.00002210407,0.000007351603,0.00001027809,0.00003027695],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001004536,0.00001262589,0.0001953792,0.00001598799,0.000001647637,0.00002766137,0.000009269003,0.00003373444,0.9990022,0.00005804719,0.00007875775,0.0004641384],"study_design_scores_gemma":[0.00001197505,0.00006259554,0.00643739,0.000006958828,0.000007810005,0.00005476017,0.00004143839,0.0007876464,0.9905013,0.00003727807,0.002046016,0.000004967476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949803,0.0007471726,0.0007283923,0.00008113731,0.00003477115,0.0000136967,0.001399013,0.0001199246,0.001895656],"genre_scores_gemma":[0.9959891,0.0002901537,0.0005186285,0.0000563327,0.00000625407,0.00001470034,0.001117508,0.00006548933,0.001941746],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001863874,"threshold_uncertainty_score":0.00452292,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01592466542291739,"score_gpt":0.2359177794927986,"score_spread":0.2199931140698812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}