{"id":"W3024157668","doi":"10.1016/j.redox.2020.101577","title":"Trans, trans-2,4-decadienal impairs vascular endothelial function by inducing oxidative/nitrative stress and apoptosis","year":2020,"lang":"en","type":"article","venue":"Redox Biology","topic":"Antioxidant Activity and Oxidative Stress","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"National Key Research and Development Program of China; Distinguished Professor of Liaoning Province; National Natural Science Foundation of China","keywords":"Oxidative stress; Umbilical vein; Endothelial dysfunction; Peroxynitrite; Apoptosis; Endothelium; Endocrinology; Internal medicine; Chemistry; Blood pressure; Oxidative phosphorylation; Superoxide; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001372579,0.000270148,0.0005222217,0.00007995669,0.0001483186,0.00001528285,0.00008284563,0.0002658548,0.0002040017],"category_scores_gemma":[0.0001106081,0.0002256207,0.0001525294,0.0002136826,0.0003603272,0.000172091,0.0000224289,0.0004367601,0.000006232357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000295867,"about_ca_system_score_gemma":0.00005874825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001143219,"about_ca_topic_score_gemma":0.00001937998,"domain_scores_codex":[0.9984341,0.0002492088,0.0002716332,0.0005547433,0.0001326155,0.0003577121],"domain_scores_gemma":[0.999275,0.0001734164,0.00009715368,0.0001334562,0.00007070911,0.0002502544],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009361238,0.0001574479,0.01307309,0.0001356109,0.000455049,0.000006556684,0.002728371,0.000002235426,0.9702206,0.0003571565,0.0002627828,0.01166503],"study_design_scores_gemma":[0.006840129,0.005058598,0.02804008,0.000230229,0.0006674322,0.00002927991,0.004113376,0.0002829663,0.934626,0.0002590441,0.01917363,0.0006792101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9683662,0.0008906459,0.02654425,0.002410779,0.0001272334,0.0004360352,0.0003643811,0.000095722,0.0007647274],"genre_scores_gemma":[0.9979318,0.0006316603,0.0002666246,0.000591859,0.0002552017,0.00002286198,0.0002251347,0.00002391182,0.00005092973],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03559452,"threshold_uncertainty_score":0.9200546,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01701072173204848,"score_gpt":0.2570231509950068,"score_spread":0.2400124292629583,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}