{"id":"W3024180170","doi":"10.1007/s40120-020-00191-7","title":"Quality of Life Improves with Alemtuzumab Over 6 Years in Relapsing-Remitting Multiple Sclerosis Patients with or without Autoimmune Thyroid Adverse Events: Post Hoc Analysis of the CARE-MS Studies","year":2020,"lang":"en","type":"article","venue":"Neurology and Therapy","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Sanofi","keywords":"Medicine; Expanded Disability Status Scale; Alemtuzumab; Multiple sclerosis; Thyroid; Adverse effect; Quality of life (healthcare); Internal medicine; Post-hoc analysis; Visual analogue scale; Health related quality of life; Physical therapy; Immunology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006838141,0.0006126682,0.001828062,0.0006851863,0.0003383934,0.0007840851,0.0004469184,0.0004516059,0.001157149],"category_scores_gemma":[0.006387119,0.0002025309,0.003985695,0.0007762371,0.0003511273,0.0006492516,0.0007488675,0.0007079455,0.0001102398],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003955414,"about_ca_system_score_gemma":0.0005374165,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008379511,"about_ca_topic_score_gemma":0.001747868,"domain_scores_codex":[0.9954377,0.003057982,0.0004090357,0.0004571209,0.0003755234,0.0002626611],"domain_scores_gemma":[0.9954579,0.001788057,0.001524293,0.0004044632,0.0004286172,0.0003967313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2764676,0.001575742,0.6464689,0.0009596125,0.03386688,0.0001800153,0.0003060519,0.001132087,0.002385561,0.00007582503,0.001147512,0.03543429],"study_design_scores_gemma":[0.008687986,0.03333259,0.9463614,0.00005847296,0.00856634,0.0001975308,0.0001143192,0.001053632,0.000575378,0.0001096908,0.000910939,0.00003170754],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966393,0.002473163,0.0001156161,0.00004982285,0.00002505558,0.00006553045,0.0003618432,0.000007142333,0.0002625629],"genre_scores_gemma":[0.9988908,0.0002180396,0.0001164408,0.00005054779,0.00003451079,0.00006694681,0.0005035642,0.00000220163,0.0001169309],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006838141,"threshold_uncertainty_score":0.03616399,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05676913280950129,"score_gpt":0.3111541731663431,"score_spread":0.2543850403568418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}