{"id":"W3024257894","doi":"10.1111/imm.13207","title":"Circles of Life: linking metabolic and epigenetic cycles to immunity","year":2020,"lang":"en","type":"review","venue":"Immunology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Cancer Institute; Case Comprehensive Cancer Center, Case Western Reserve University; Cancer Research Institute","keywords":"Epigenetics; Epigenome; Biology; Metabolome; DNA methylation; Epigenomics; Histone; Function (biology); Epigenetic regulation of neurogenesis; Cell biology; Genetics; Metabolomics; DNA; Gene; Histone methyltransferase; Bioinformatics; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003989557,0.0007565813,0.0007924284,0.001670913,0.0004437294,0.001355068,0.0006948913,0.001337149,0.005947231],"category_scores_gemma":[0.0006969685,0.0001964698,0.0002723031,0.001649161,0.000739997,0.001959566,0.0009859984,0.001831905,0.003136774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008834873,"about_ca_system_score_gemma":0.001089603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006857952,"about_ca_topic_score_gemma":0.001150979,"domain_scores_codex":[0.9998744,0.00003003429,0.00001219569,0.0000225629,0.00004393193,0.00001689535],"domain_scores_gemma":[0.9997805,0.0001032008,0.00002472389,0.000008574591,0.00005054637,0.00003259136],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005176576,0.00002825075,0.0001369334,0.008027205,0.00003913407,0.0002297636,0.0001485201,0.0002610405,0.001821192,0.02201628,0.05464278,0.9125972],"study_design_scores_gemma":[0.000002349993,0.00001845204,0.0002403538,0.001049613,0.00001395314,0.0005323566,0.00005057572,0.00003016992,0.0001839547,0.004101892,0.9937687,0.000007743792],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001071564,0.9951433,0.0003239125,0.0009575305,0.0007194538,0.000004394438,0.00002017097,0.00001428196,0.002709768],"genre_scores_gemma":[0.0009588698,0.9962543,0.0002777936,0.0004136088,0.0005200743,0.000007114989,0.00003096021,0.000003249431,0.001533941],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005947231,"threshold_uncertainty_score":0.01989549,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02954830110085185,"score_gpt":0.312405647996345,"score_spread":0.2828573468954931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}