{"id":"W3024275141","doi":"10.3389/fnmol.2020.00067","title":"D1 Dopamine Receptor Activation Induces Neuronal eEF2 Pathway-Dependent Protein Synthesis","year":2020,"lang":"en","type":"article","venue":"Frontiers in Molecular Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministry of Health, State of Israel; Azrieli Foundation; Israel Science Foundation; International Development Research Centre; Canadian Institutes of Health Research; EU Joint Programme – Neurodegenerative Disease Research","keywords":"Dopamine; Dopamine receptor D1; Dopamine receptor; Dopamine receptor D3; Biology; Neuroscience; Dephosphorylation; Dopamine receptor D2; Cell biology; Translation (biology); Dopaminergic; Phosphorylation; Messenger RNA; Phosphatase; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009201021,0.0002935326,0.0002161134,0.0001826797,0.0001479602,0.0001674861,0.0001122021,0.0001740648,0.001116339],"category_scores_gemma":[0.00007100566,0.0001052754,0.0002596554,0.0001329157,0.0001351643,0.00009677861,0.0001506748,0.0003338229,0.0002570528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000358382,"about_ca_system_score_gemma":0.0001932091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00115122,"about_ca_topic_score_gemma":0.003177132,"domain_scores_codex":[0.9999397,0.000006797136,0.000005537269,0.00001724375,0.00001164114,0.00001905439],"domain_scores_gemma":[0.9999646,0.000006922875,0.000008888707,0.000004714566,0.000004351188,0.0000104085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001446214,0.00002417182,0.0001148925,0.00003909028,0.000006174142,0.00004224487,0.00000706576,0.00002681493,0.9984177,0.00006859256,0.00005293774,0.001055725],"study_design_scores_gemma":[0.00002056857,0.0001981312,0.007406717,0.000006204804,0.000009320538,0.0002096712,0.00002303373,0.0003666157,0.9894871,0.00005420503,0.002214422,0.000004062444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910609,0.002836995,0.002193962,0.0001419986,0.00004075676,0.00003570398,0.0008841858,0.00006831504,0.002737316],"genre_scores_gemma":[0.9866131,0.00263052,0.002950007,0.00009329908,0.00001301657,0.00008097736,0.001777424,0.00002698845,0.005814589],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00115122,"threshold_uncertainty_score":0.003734529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01306243323811387,"score_gpt":0.2131784029865058,"score_spread":0.200115969748392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}