{"id":"W3024289774","doi":"10.1007/s11538-020-00737-8","title":"A Mathematical Model for the Kinetics of the MalFGK$$_2$$ Maltose Transporter","year":2020,"lang":"en","type":"article","venue":"Bulletin of Mathematical Biology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Transporter; Function (biology); Maltose; Kinetics; Biological system; ATP-binding cassette transporter; Chemistry; Steady state (chemistry); Thermodynamics; Biology; Biochemistry; Physics; Enzyme; Physical chemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008620868,0.0009554474,0.001865834,0.0008636251,0.0008935895,0.002481371,0.002647723,0.003523193,0.007535696],"category_scores_gemma":[0.002825583,0.0005898323,0.001739353,0.0009922349,0.001637635,0.002516723,0.00150886,0.002260208,0.001266571],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002673595,"about_ca_system_score_gemma":0.002436394,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01073763,"about_ca_topic_score_gemma":0.004801123,"domain_scores_codex":[0.999608,0.000116742,0.00002047385,0.00008561341,0.00008219774,0.00008696927],"domain_scores_gemma":[0.9992456,0.0004267395,0.0001018173,0.00002924192,0.0001332807,0.00006331306],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00003909326,0.00004273362,0.0003840187,0.0001219837,0.00003995466,0.000231174,0.0001264553,0.4784967,0.003040006,0.5116131,0.002446606,0.003418074],"study_design_scores_gemma":[0.00001841828,0.00001482839,0.0001000511,0.000009785877,0.00001350133,0.0000619692,0.00001562929,0.9500374,0.0001494065,0.04778777,0.00177207,0.00001926076],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.06202176,0.0042707,0.8686957,0.009199515,0.0006107984,0.0001270603,0.001050886,0.0003141681,0.0537094],"genre_scores_gemma":[0.8431733,0.004165825,0.06470338,0.001509829,0.0005154044,0.000670667,0.000735758,0.0002157362,0.08431012],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01073763,"threshold_uncertainty_score":0.02520943,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03533413261060365,"score_gpt":0.262483768464888,"score_spread":0.2271496358542843,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}