{"id":"W3024324725","doi":"10.3389/fonc.2020.00727","title":"Insulin Growth Factor Binding Protein 7 (IGFBP7)-Related Cancer and IGFBP3 and IGFBP7 Crosstalk","year":2020,"lang":"en","type":"review","venue":"Frontiers in Oncology","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":120,"is_retracted":false,"has_abstract":true,"ca_institutions":"Stollery Children's Hospital; Alberta Hospital Edmonton; University of Alberta","funders":"Hubei University; Hubei University of Medicine; Austrian Science Fund; Children's Health Research Institute; Women and Children's Health Research Institute; Canadian Institutes of Health Research; Hubei University of Technology; Cancer Research Society; Children's Hospital Foundation; Stollery Children’s Hospital Foundation; Cancer Research Institute","keywords":"IGFBP3; Insulin-like growth factor-binding protein; Crosstalk; Cancer research; Growth factor; Carcinogenesis; Biology; Proteases; Cancer; Insulin-like growth factor; Bioinformatics; Cell biology; Receptor; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003131369,0.0005669719,0.0005999531,0.001703761,0.0002090094,0.0006870528,0.0004259394,0.0006400522,0.003744346],"category_scores_gemma":[0.000508527,0.0001505444,0.0004539797,0.001583549,0.0002205292,0.000570927,0.0004004853,0.001021533,0.001250183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005589584,"about_ca_system_score_gemma":0.001180726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001531955,"about_ca_topic_score_gemma":0.003029617,"domain_scores_codex":[0.9998797,0.00001985132,0.0000176164,0.00001858226,0.00004755684,0.00001668196],"domain_scores_gemma":[0.9998274,0.00006992251,0.00002471807,0.000004252446,0.00005862773,0.00001515228],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001392497,0.00005295984,0.0004826569,0.02183776,0.0001841316,0.0003695866,0.00008756769,0.000291626,0.003352399,0.003193383,0.03163678,0.938372],"study_design_scores_gemma":[0.00001622236,0.00007315215,0.001699655,0.003057424,0.0002220481,0.002054181,0.00007545763,0.00008807146,0.0009971689,0.001418875,0.9902794,0.00001838644],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002446409,0.9979578,0.0001460216,0.0002833265,0.0002192917,0.00000353998,0.00003955732,0.000009124877,0.00109663],"genre_scores_gemma":[0.0013824,0.9973189,0.0002334113,0.0001925187,0.0001271337,0.000004064032,0.00009427542,0.000001579277,0.0006456246],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003744346,"threshold_uncertainty_score":0.01252604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03283309997072823,"score_gpt":0.3285932222651643,"score_spread":0.295760122294436,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}