{"id":"W3024969630","doi":"10.14309/ajg.0000000000002128","title":"Ursodeoxycholic Acid Treatment–Induced GLOBE Score Changes Are Associated With Liver Transplantation-Free Survival in Patients With Primary Biliary Cholangitis","year":2022,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Toronto General Hospital; University Health Network","funders":"European Association for the Study of the Liver; Stichting voor Lever- en Maag-Darm Onderzoek; Gilead Sciences; Intercept Pharmaceuticals; Dr. Falk Pharma; GlaxoSmithKline; National Institute for Health and Care Research; Falk Foundation","keywords":"Medicine; Hazard ratio; Interquartile range; Confidence interval; Globe; Internal medicine; Liver transplantation; Ursodeoxycholic acid; Proportional hazards model; Gastroenterology; Cohort; Transplantation; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004897219,0.0001872398,0.0002648727,0.0002933949,0.0001593053,0.0003733366,0.0001704638,0.0002300704,0.001180792],"category_scores_gemma":[0.001645062,0.000144677,0.0005212034,0.0005282132,0.0002216705,0.0002009566,0.000328392,0.0004637153,0.0001349982],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001877124,"about_ca_system_score_gemma":0.000218229,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001070357,"about_ca_topic_score_gemma":0.001411275,"domain_scores_codex":[0.9997488,0.00008049079,0.00002658147,0.00004302642,0.00005031157,0.00005089637],"domain_scores_gemma":[0.9988515,0.000257428,0.0005983845,0.00007553097,0.00007271242,0.000144373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002466351,0.00001010969,0.998472,0.000005372625,0.00004782727,0.000040819,0.000009834424,0.00007000642,0.0001089956,0.000005761617,0.00003695572,0.0009455609],"study_design_scores_gemma":[0.00000835557,0.00008219469,0.9993507,0.000002965075,0.00003491828,0.0001389211,0.00002140893,0.0002351243,0.00004485855,0.00001631844,0.00006227897,0.000001881435],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993662,0.0003067787,0.00004267834,0.00002641798,0.000003068808,0.000001843957,0.00008606804,0.000002340127,0.0001644737],"genre_scores_gemma":[0.99972,0.0000635371,0.00002067304,0.000007261171,0.00000520823,0.000001307261,0.0001380922,7.039779e-7,0.0000431909],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001180792,"threshold_uncertainty_score":0.003950179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01413124465000412,"score_gpt":0.2211786614303297,"score_spread":0.2070474167803255,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}