{"id":"W3025067441","doi":"10.1111/his.14096","title":"Loss of switch/sucrose non‐fermenting complex protein expression in undifferentiated gastrointestinal and pancreatic carcinomas","year":2020,"lang":"en","type":"article","venue":"Histopathology","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC; BC Cancer Agency; University of Calgary; University of Alberta Hospital; University of Alberta; Vancouver General Hospital; University of British Columbia","funders":"","keywords":"SMARCA4; SMARCB1; ARID1A; MSH6; Biology; Pathology; MSH2; Gastrointestinal tract; Immunohistochemistry; Pancreas; Adenocarcinoma; Cancer research; Medicine; Chromatin remodeling; Cancer; Colorectal cancer; Endocrinology; Mutation; Epigenetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007348456,0.0001156478,0.00020759,0.00002944903,0.00003359382,0.000004305569,0.00008479507,0.0000600164,0.00001688448],"category_scores_gemma":[0.00006601927,0.0001134438,0.00003431169,0.0000526964,0.0001059113,0.000002036486,0.0001043304,0.00008398788,0.000001479461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001393062,"about_ca_system_score_gemma":0.0000341635,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002873918,"about_ca_topic_score_gemma":0.000014191,"domain_scores_codex":[0.9991746,0.00006305326,0.0002413012,0.0002877221,0.00005938841,0.000173956],"domain_scores_gemma":[0.9996551,0.000005950358,0.0001086088,0.0001387319,0.00003421429,0.00005738276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001071922,0.00003097993,0.07240795,0.0001057206,0.00000100324,0.00002678936,0.0002171185,0.00003087711,0.9269027,0.000006588621,0.00003881663,0.0001242355],"study_design_scores_gemma":[0.002717793,0.001063178,0.5958927,0.0003100048,0.00003039071,0.0003159618,0.0002114803,0.005354886,0.393301,0.00009907655,0.000352065,0.0003514664],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958931,0.0003501614,0.003343009,0.00008668102,0.00001695903,0.0001542401,0.000007830489,0.000008646955,0.0001393505],"genre_scores_gemma":[0.996214,0.00001033471,0.003515151,0.00008235437,0.00004229608,0.00001611886,0.00004948887,0.0000138782,0.00005636033],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5336017,"threshold_uncertainty_score":0.4626102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01863937932496458,"score_gpt":0.2388900008190841,"score_spread":0.2202506214941195,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}