{"id":"W3025634964","doi":"10.1080/23723556.2020.1758540","title":"NORRIN plays a context-dependent role in glioblastoma stem cells","year":2020,"lang":"en","type":"article","venue":"Molecular & Cellular Oncology","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; Cancer Research Society","keywords":"Glioblastoma; Context (archaeology); Wnt signaling pathway; Stem cell; Phenotype; Cancer stem cell; Biology; Cancer research; Cell biology; Genetics; Signal transduction; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001667041,0.0003001499,0.0004119059,0.00007369476,0.00005216958,0.0000212615,0.0004013148,0.0005293737,0.00005923559],"category_scores_gemma":[0.00001456067,0.0002956764,0.0002427959,0.0002119434,0.0001097123,0.000004635153,0.000234276,0.000383576,0.0001775292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009993619,"about_ca_system_score_gemma":0.0002327542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007657627,"about_ca_topic_score_gemma":0.0001090831,"domain_scores_codex":[0.9978894,0.0002334968,0.0004137918,0.0007214484,0.0002257423,0.0005161316],"domain_scores_gemma":[0.999166,0.00001256666,0.0001270752,0.0003558461,0.00005658603,0.0002818888],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004776451,0.0001124345,0.0001178651,0.00002698588,0.0001385958,0.0009085868,0.000288767,0.003325188,0.9842399,0.0000695967,0.0006042907,0.009690181],"study_design_scores_gemma":[0.001650412,0.001538561,0.000007115701,0.00001277895,0.00003918564,0.00003436423,0.0004065257,0.0004560048,0.8752849,0.00002190326,0.1202437,0.0003045143],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866229,0.006181403,0.003240657,0.0007907288,0.0002558386,0.0004053136,0.00001694487,0.00003170108,0.002454467],"genre_scores_gemma":[0.9961975,0.0002186284,0.00009903048,0.002827227,0.0001584078,0.00005256389,0.00002023023,0.00005460513,0.0003717833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1196394,"threshold_uncertainty_score":0.9999495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006757491000409226,"score_gpt":0.2145632352190125,"score_spread":0.2078057442186032,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}