{"id":"W3025668491","doi":"10.1016/j.neo.2020.04.002","title":"Alternative splicing of LSD1+8a in neuroendocrine prostate cancer is mediated by SRRM4","year":2020,"lang":"en","type":"article","venue":"Neoplasia","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Janssen Biotech; Canadian Institutes of Health Research; Astellas Pharma Global Development; Lucas Foundation; U.S. Department of Defense; Gilead Sciences; National Cancer Institute; National Institutes of Health; Prostate Cancer Foundation; Institute for Prostate Cancer Research; Bayer Corporation","keywords":"Prostate cancer; Prostate; RNA splicing; Alternative splicing; Cancer; Cancer research; Biology; Immunohistochemistry; Oncology; Internal medicine; Medicine; Computational biology; Bioinformatics; Gene; Genetics; Exon","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001605181,0.0001514118,0.0001361207,0.0002052612,0.0001329083,0.000231337,0.0001299883,0.0001638403,0.001175918],"category_scores_gemma":[0.0001588814,0.0001296474,0.0003110339,0.0001334264,0.0002221764,0.0001154109,0.0001608222,0.0002518256,0.0004882947],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002325531,"about_ca_system_score_gemma":0.0001762611,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006232763,"about_ca_topic_score_gemma":0.001333605,"domain_scores_codex":[0.9998738,0.00002260968,0.000009707493,0.00003269743,0.00003830252,0.00002300117],"domain_scores_gemma":[0.9998732,0.00001824693,0.00004989474,0.00001698649,0.00001727132,0.00002440564],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001487686,0.00001352094,0.008399734,0.00004434336,0.00001832184,0.0004323804,0.00004118524,0.0001131622,0.9887236,0.0001391623,0.00006506978,0.001860853],"study_design_scores_gemma":[0.00002930624,0.0005303829,0.1613476,0.00001307233,0.00005556364,0.005471724,0.0002322372,0.001938849,0.8239137,0.0002004828,0.006246843,0.00002030985],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974293,0.0006762443,0.0009156442,0.00004350411,0.000006258701,0.000005190788,0.0002010334,0.00004041632,0.0006822984],"genre_scores_gemma":[0.9971436,0.0003186829,0.001013719,0.00002608637,0.00000266591,0.00000592016,0.0004747194,0.000008511853,0.001006063],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001175918,"threshold_uncertainty_score":0.003933787,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02428665237256586,"score_gpt":0.3207135677435231,"score_spread":0.2964269153709572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}