{"id":"W3025850903","doi":"10.1016/j.msec.2020.111088","title":"Adhesion, intracellular signalling and osteogenic differentiation of mesenchymal progenitor cells and preosteoblasts on poly(epsilon)caprolactone films functionalized by peptides derived from fibronectin and/or BMP-9","year":2020,"lang":"en","type":"article","venue":"Materials Science and Engineering C","topic":"Bone Tissue Engineering Materials","field":"Engineering","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Mesenchymal stem cell; Cell biology; Bone morphogenetic protein 2; Fibronectin; Chemistry; RUNX2; Progenitor cell; Adhesion; SMAD; Osteoblast; Cell adhesion; Stem cell; Signal transduction; Biochemistry; Extracellular matrix; Biology; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000159733,0.0002424921,0.0001539004,0.0001660898,0.0001514379,0.0002694003,0.0002070308,0.0002547304,0.001507425],"category_scores_gemma":[0.00017806,0.0001960379,0.0001832465,0.0001455797,0.0001620843,0.0001773537,0.0001332037,0.0003356567,0.000262786],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002373753,"about_ca_system_score_gemma":0.0001839311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001048002,"about_ca_topic_score_gemma":0.001822733,"domain_scores_codex":[0.9998176,0.00002415298,0.00001542668,0.00002327625,0.00005465798,0.00006491903],"domain_scores_gemma":[0.9998748,0.00005333555,0.00002352762,0.000009827722,0.00001620147,0.00002228802],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001534504,0.00001635479,0.0001085374,0.00002518161,0.000003521641,0.00006022686,0.00003063317,0.0001032094,0.9989362,0.00005669111,0.00003035076,0.0004754977],"study_design_scores_gemma":[0.00002334606,0.0001244456,0.005093663,0.000005177141,0.00001307616,0.00006788639,0.00005811866,0.001026966,0.9928308,0.00003005579,0.0007206242,0.000005961689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969497,0.0004795975,0.0005117378,0.00003618603,0.00002455683,0.000008412263,0.0001284646,0.000009273561,0.001851936],"genre_scores_gemma":[0.9957768,0.0003719305,0.0007757675,0.00005589989,0.00001224456,0.00002318596,0.0002537202,0.000009289349,0.002721118],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001507425,"threshold_uncertainty_score":0.005042851,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00943906543907522,"score_gpt":0.184416272199291,"score_spread":0.1749772067602157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}