{"id":"W3025958141","doi":"10.1364/boe.392722","title":"Novel quantitative signature of tumor stromal architecture: polarized light imaging differentiates between myxoid and sclerotic human breast cancer stroma","year":2020,"lang":"en","type":"article","venue":"Biomedical Optics Express","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Canada Research Chairs; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Stroma; Stromal cell; Breast cancer; Ductal carcinoma; Pathology; Medicine; Cancer; Immunohistochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009823812,0.0002799121,0.0007212943,0.0001239803,0.00008343309,0.0000356474,0.0001787264,0.00009784796,0.0001550122],"category_scores_gemma":[0.00006643045,0.0002179527,0.0001417337,0.0002582972,0.0004058135,0.00005923791,0.0001795692,0.0004552072,0.000001288856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003384267,"about_ca_system_score_gemma":0.0001117949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001578383,"about_ca_topic_score_gemma":0.000004060455,"domain_scores_codex":[0.9981153,0.00004370002,0.0004531535,0.0004450326,0.0005656497,0.0003771867],"domain_scores_gemma":[0.9987403,0.0001098793,0.0001998235,0.0001987396,0.0001187237,0.000632602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002758515,0.0002194122,0.008280095,0.000540581,0.0002889116,0.00003141202,0.0007997301,0.000001206119,0.9878658,0.0002068061,0.0001827762,0.001307405],"study_design_scores_gemma":[0.03138288,0.003527885,0.6760378,0.00389106,0.004404953,0.0002475219,0.002352523,0.002494921,0.2700263,0.0003235467,0.003412565,0.001898016],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.973667,0.001702474,0.01447891,0.007846704,0.0001461154,0.0004703439,0.001574969,0.00006276696,0.00005076306],"genre_scores_gemma":[0.9866636,0.00003924747,0.01232157,0.0003107346,0.0004830894,0.00001549329,0.0001062749,0.0000429664,0.00001699122],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7178395,"threshold_uncertainty_score":0.8887853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02607979616435189,"score_gpt":0.2859927855896546,"score_spread":0.2599129894253027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}