{"id":"W3026272931","doi":"10.4049/immunohorizons.2000014","title":"FHL2 Is Essential for Spleen T Cell–Dependent B Cell Activation and Antibody Response","year":2020,"lang":"en","type":"article","venue":"ImmunoHorizons","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Germinal center; Spleen; Biology; Molecular biology; B cell; Cytidine deaminase; Plasma cell; Immune system; Activation-induced (cytidine) deaminase; Cell biology; Immunoglobulin class switching; Antibody; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000137968,0.0006095312,0.0002313562,0.0003504884,0.0002210017,0.000324472,0.0003151859,0.0004575361,0.002171847],"category_scores_gemma":[0.0001670528,0.0002018954,0.0002903811,0.0001200373,0.0002597767,0.0001371091,0.0003663909,0.000486337,0.001234337],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003209007,"about_ca_system_score_gemma":0.0002004954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007528636,"about_ca_topic_score_gemma":0.0007206241,"domain_scores_codex":[0.9997855,0.00003705996,0.00002510215,0.00004716008,0.00006118721,0.00004405372],"domain_scores_gemma":[0.9996462,0.00004148809,0.0001135822,0.00003228243,0.0000270319,0.0001394119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005766465,0.00001167464,0.0001516372,0.00001661035,0.000002120493,0.00008772599,0.000004767267,0.00001786732,0.999347,0.00002705558,0.00002810386,0.0002476412],"study_design_scores_gemma":[0.00004264509,0.000110792,0.01245263,0.00001118057,0.00001654499,0.0009563113,0.00003753334,0.00150058,0.9817895,0.00004756818,0.003024647,0.00001011686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927423,0.0008470971,0.003564037,0.0001129587,0.00003914711,0.00003092777,0.001202286,0.0002534751,0.001207702],"genre_scores_gemma":[0.9942888,0.000168604,0.001377231,0.00005352232,0.00001517896,0.00003263953,0.001253953,0.00005643102,0.002753578],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002171847,"threshold_uncertainty_score":0.007265568,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01184452117589917,"score_gpt":0.2591369629171257,"score_spread":0.2472924417412266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}