{"id":"W3026272931","doi":"10.4049/immunohorizons.2000014","title":"FHL2 Is Essential for Spleen T Cell–Dependent B Cell Activation and Antibody Response","year":2020,"lang":"en","type":"article","venue":"ImmunoHorizons","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Germinal center; Spleen; Biology; Molecular biology; B cell; Cytidine deaminase; Plasma cell; Immune system; Activation-induced (cytidine) deaminase; Cell biology; Immunoglobulin class switching; Antibody; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001986358,0.000202101,0.0002345903,0.00009012024,0.0003384552,0.00005155744,0.0001477346,0.000228211,0.001249821],"category_scores_gemma":[0.00008833871,0.000202379,0.0001185426,0.0001096125,0.00007666558,0.0002376683,0.00008368294,0.0003055778,0.0008170065],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003890301,"about_ca_system_score_gemma":0.00007234655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008752212,"about_ca_topic_score_gemma":7.990466e-7,"domain_scores_codex":[0.9988096,0.0001795088,0.0003103126,0.0003689806,0.0000428659,0.0002887124],"domain_scores_gemma":[0.9993088,0.0002088353,0.000132042,0.0002238753,0.0000941578,0.00003232787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004693425,0.0001027813,0.00007029548,0.00002671394,0.00008612341,8.476247e-7,0.0009378053,0.000002622126,0.9715871,0.00005182076,0.02151961,0.0009208377],"study_design_scores_gemma":[0.001920582,0.0005638962,0.0006415385,0.000009221651,0.00005896619,0.000009702476,0.0006598248,0.00004494776,0.7936081,0.0000118033,0.2022828,0.0001886587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9778048,0.001268771,0.01159299,0.003864447,0.002958032,0.0006517952,0.00004715168,0.000146282,0.001665783],"genre_scores_gemma":[0.9854186,0.0001436831,0.0001120852,0.0007829953,0.00008818262,0.00003684502,0.0003072679,0.00003126087,0.01307905],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1807632,"threshold_uncertainty_score":0.999961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01184452117589917,"score_gpt":0.2591369629171257,"score_spread":0.2472924417412266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}