{"id":"W3026559828","doi":"10.1371/journal.ppat.1008393","title":"Discordant rearrangement of primary and anamnestic CD8+ T cell responses to influenza A viral epitopes upon exposure to bacterial superantigens: Implications for prophylactic vaccination, heterosubtypic immunity and superinfections","year":2020,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; Immunology; Influenza A virus; Vaccination; Virology; Microbiology; Immunization; Immunodominance; Epitope; Immune system; T cell; Virus; Antigen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001543812,0.0001392911,0.0001546597,0.0001176452,0.00007976644,0.0002022438,0.0001104838,0.0002230479,0.0008059299],"category_scores_gemma":[0.0001864102,0.0001022487,0.0001163276,0.00006393855,0.0001932935,0.0001241904,0.0001320952,0.0004499908,0.0001927004],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001055914,"about_ca_system_score_gemma":0.00008852204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001236955,"about_ca_topic_score_gemma":0.0001754646,"domain_scores_codex":[0.999851,0.0000247113,0.00001559658,0.00003906244,0.00002214456,0.00004743761],"domain_scores_gemma":[0.999856,0.00003390712,0.00002914729,0.00002315743,0.00001675455,0.00004089555],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002098196,0.00002271821,0.001445866,0.00001635514,0.000001842504,0.00004352294,0.00002527067,0.00002202907,0.997045,0.00002969706,0.00001443147,0.001123446],"study_design_scores_gemma":[0.00004246099,0.002307535,0.1693565,0.00001726863,0.00002842232,0.001659664,0.0002783932,0.001009711,0.8234617,0.0002337888,0.001593326,0.00001111131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989697,0.0002531635,0.0003085429,0.00001629044,0.00000678495,0.000006307837,0.00006215082,0.00001159744,0.0003654542],"genre_scores_gemma":[0.9992167,0.00009418809,0.0002049467,0.0000376495,0.000005013833,0.00001070729,0.00009218136,0.000003328549,0.0003353076],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008059299,"threshold_uncertainty_score":0.002696157,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08858217394586541,"score_gpt":0.3340202231571055,"score_spread":0.2454380492112401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}