{"id":"W3026609319","doi":"10.1016/j.jaci.2020.03.012","title":"Multiomic approaches to study B cells: Sequencing, cytometry, imaging, and beyond","year":2020,"lang":"en","type":"letter","venue":"Journal of Allergy and Clinical Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Imperial College London; Innovationsfonden","keywords":"Immunoglobulin E; Immunology; Memory B cell; Allergen; Allergy; Antibody; Flow cytometry; Biology; Medicine; B cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007158328,0.0007512931,0.001102519,0.0006630724,0.00106774,0.002467322,0.001467394,0.01810512,0.0034526],"category_scores_gemma":[0.01081609,0.0005206488,0.0009164237,0.0002823435,0.00312646,0.003364314,0.001110865,0.02368182,0.002384837],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001664306,"about_ca_system_score_gemma":0.001031054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008916589,"about_ca_topic_score_gemma":0.001819053,"domain_scores_codex":[0.9966145,0.001417853,0.000310135,0.0003443897,0.001023104,0.0002900361],"domain_scores_gemma":[0.9834802,0.01197619,0.0004048069,0.0006200155,0.002153792,0.001365006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006772044,0.0002396,0.002574038,0.0003803119,0.0001062341,0.00353215,0.0002313749,0.0003283554,0.01053454,0.01193655,0.83236,0.1370997],"study_design_scores_gemma":[0.0003900802,0.0004112064,0.003128177,0.0003936371,0.00009737675,0.008046483,0.0005625022,0.003652614,0.007587649,0.07829604,0.8973027,0.0001314473],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001753385,0.01653854,0.005872671,0.9445474,0.02840017,0.0000466708,0.0000745156,0.0001173425,0.002649321],"genre_scores_gemma":[0.0299107,0.01922528,0.01118944,0.8198568,0.1097195,0.0002488452,0.00007125885,0.00008299537,0.009695248],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01810512,"threshold_uncertainty_score":0.03785729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06624090990640441,"score_gpt":0.2886076183899619,"score_spread":0.2223667084835575,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}