{"id":"W3026962176","doi":"10.1172/jci127668","title":"Blocking endothelial apoptosis revascularizes the retina in a model of ischemic retinopathy","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Eye Institute; National Health and Medical Research Council; Australian Research Council; Genentech; National Institutes of Health; Royal Society; Korea Advanced Institute of Science and Technology; British Heart Foundation; University of Toronto; Medical Research Council; Peter MacCallum Cancer Centre; Francis Crick Institute; Australian Government; University of Texas Southwestern Medical Center","keywords":"Retina; Retinal; Hypoxia (environmental); Neovascularization; Ischemia; Retinopathy; Diabetic retinopathy; Apoptosis; Biology; Ophthalmology; Angiogenesis; Medicine; Cancer research; Internal medicine; Chemistry; Endocrinology; Neuroscience; Diabetes mellitus; Biochemistry; Oxygen","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004702821,0.0005794471,0.0006088286,0.000511062,0.0002120578,0.0003746643,0.0003881449,0.0004888882,0.001190641],"category_scores_gemma":[0.0002216561,0.0002913217,0.0003235012,0.0002593345,0.0003342445,0.000349692,0.000186249,0.001418795,0.0002191326],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003356281,"about_ca_system_score_gemma":0.0003690286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008962888,"about_ca_topic_score_gemma":0.001314045,"domain_scores_codex":[0.9996576,0.00007047474,0.00003859253,0.00006242246,0.00008156718,0.00008939899],"domain_scores_gemma":[0.9998318,0.00002967551,0.00004636184,0.000030188,0.00001913074,0.00004279864],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007288349,0.0004928829,0.0001035322,0.0001033003,0.00001854633,0.0001052737,0.00004225835,0.0001493148,0.9933334,0.0002738515,0.0001528522,0.004495875],"study_design_scores_gemma":[0.0002311635,0.006946015,0.00271919,0.00002186769,0.00005703779,0.0004765161,0.00004748446,0.002741309,0.983812,0.000176291,0.002759959,0.00001114163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868663,0.004201687,0.004916959,0.0004392606,0.0001857074,0.0001273442,0.0001866472,0.0002706414,0.002805426],"genre_scores_gemma":[0.9856967,0.003181215,0.005594562,0.0002232249,0.00005472807,0.0001497252,0.0003336372,0.00003649739,0.004729653],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001190641,"threshold_uncertainty_score":0.00398308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1172051813002609,"score_gpt":0.3667807011063106,"score_spread":0.2495755198060496,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}