{"id":"W3027094359","doi":"10.1016/j.jcyt.2020.03.096","title":"Design of a confirmatory pivotal study with intramyocardial GCSF-mobilized autologous CD34 cells (CLBS14) for the treatment of an orphan-sized population with no-option refractory disabling angina","year":2020,"lang":"en","type":"article","venue":"Cytotherapy","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Medicine; Angina; Population; Canadian Cardiovascular Society; Refractory (planetary science); Revascularization; Internal medicine; Physical therapy; Intensive care medicine; Cardiology; Myocardial infarction; Environmental health","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01654376,0.004521522,0.003702826,0.0006321808,0.001260837,0.002478189,0.002044848,0.004622319,0.009105669],"category_scores_gemma":[0.01223089,0.001444021,0.003524902,0.0006866489,0.003118416,0.001789464,0.0009741492,0.005174349,0.00239598],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001787787,"about_ca_system_score_gemma":0.006084427,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002098065,"about_ca_topic_score_gemma":0.002330554,"domain_scores_codex":[0.9906862,0.0066907,0.0003071744,0.0009456903,0.0003383835,0.001031882],"domain_scores_gemma":[0.9916096,0.002844872,0.001158907,0.001196259,0.0008337636,0.002356611],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"not_applicable","study_design_scores_codex":[0.9770069,0.01436604,0.002031559,0.0001178574,0.0004778803,0.0000995602,0.00005853462,0.0006444568,0.001839197,0.0003303614,0.0006841113,0.002343659],"study_design_scores_gemma":[0.6652231,0.3252659,0.003915439,0.00004300469,0.0008155886,0.00006450766,0.0001020087,0.001068745,0.0009285446,0.00063804,0.001885411,0.00004979268],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.914198,0.001309982,0.00389924,0.00252974,0.001922112,0.06701373,0.003854918,0.00009656591,0.005175561],"genre_scores_gemma":[0.94169,0.0006490388,0.005982058,0.002791425,0.002017887,0.04036805,0.003169209,0.00004191899,0.003290551],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.01654376,"threshold_uncertainty_score":0.08749282,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2191309407913918,"score_gpt":0.3852911665710117,"score_spread":0.1661602257796199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}