{"id":"W3027146212","doi":"10.1038/s41467-020-16431-1","title":"Intestinal fungi are causally implicated in microbiome assembly and immune development in mice","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":250,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotchkiss Brain Institute; Alberta Children's Hospital; Université de Sherbrooke; University of Calgary","funders":"Canadian Institutes of Health Research; W. Garfield Weston Foundation; Canada Foundation for Innovation; Government of Canada","keywords":"Microbiome; Immune system; Biology; Colonization; Inflammation; Microbiology; Immunology; Dysbiosis; Bacteria; Acquired immune system; Colitis; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005930529,0.0008490931,0.0004686241,0.001746181,0.0004600204,0.0009093804,0.0005503732,0.001480008,0.002893825],"category_scores_gemma":[0.0003281954,0.0007823301,0.0006890232,0.0005348996,0.0008767733,0.0007195494,0.0006552025,0.002473517,0.0008015182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005314549,"about_ca_system_score_gemma":0.0004719635,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000756355,"about_ca_topic_score_gemma":0.001418542,"domain_scores_codex":[0.9991381,0.0001530858,0.00007457336,0.0002368052,0.000188148,0.0002092597],"domain_scores_gemma":[0.998916,0.0001112727,0.0004459441,0.0001135012,0.0000448404,0.000368359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001631865,0.0002731671,0.001251306,0.0000705828,0.00001853927,0.0002005066,0.00005719012,0.0001134027,0.9932019,0.0003670827,0.0001321984,0.002682248],"study_design_scores_gemma":[0.0003218976,0.00261308,0.03244984,0.00008970302,0.0001129191,0.001265747,0.0002036873,0.002235913,0.9524028,0.0007624992,0.007506334,0.00003546022],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9822676,0.003559026,0.006809274,0.0007480715,0.0001254059,0.0001288792,0.002630635,0.0005700729,0.003161153],"genre_scores_gemma":[0.9767079,0.002336991,0.009492069,0.0004886562,0.00004981043,0.0002595189,0.001648628,0.0002507366,0.008765645],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002893825,"threshold_uncertainty_score":0.009680867,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02020221515828197,"score_gpt":0.2963600732957992,"score_spread":0.2761578581375172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}