{"id":"W3027155039","doi":"10.3390/cancers12051321","title":"Insights into the Molecular Mechanisms Behind Intralesional Immunotherapies for Advanced Melanoma","year":2020,"lang":"en","type":"review","venue":"Cancers","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Melanoma; Medicine; Immune system; Metastatic melanoma; Cancer; Disease; Immunotherapy; Skin cancer; Adverse effect; Immune surveillance; Metastasis; Immunology; Cancer research; Dermatology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003443389,0.00046358,0.0006828198,0.001305045,0.0001780357,0.0006798938,0.0004321855,0.0006709298,0.003178408],"category_scores_gemma":[0.0003402139,0.0001699847,0.0004535961,0.000796113,0.0002723488,0.0008260655,0.0003790972,0.001373517,0.001414136],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003272319,"about_ca_system_score_gemma":0.0004964288,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004677505,"about_ca_topic_score_gemma":0.001108553,"domain_scores_codex":[0.9999114,0.00001650674,0.00001070883,0.00001665533,0.00003213512,0.00001252892],"domain_scores_gemma":[0.9998834,0.00005875589,0.00001614874,0.000003788433,0.00002723297,0.00001071247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009714537,0.0001292222,0.0001604569,0.01789153,0.00008546445,0.0002426075,0.00007568966,0.0004684503,0.008730561,0.005621507,0.01564022,0.9508571],"study_design_scores_gemma":[0.00002761433,0.0002689962,0.0008957414,0.003710663,0.0001587768,0.00160267,0.00005591948,0.00016125,0.002460876,0.002485049,0.9881534,0.00001905555],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000295745,0.9979925,0.0002098901,0.0002158405,0.000111573,0.000007080629,0.0000211858,0.000007361426,0.001138802],"genre_scores_gemma":[0.00155429,0.9973872,0.0002055728,0.000178076,0.00008782581,0.00001023455,0.00003231686,0.000001458574,0.0005430086],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003178408,"threshold_uncertainty_score":0.01063287,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03532092597537828,"score_gpt":0.3543734595694293,"score_spread":0.319052533594051,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}