{"id":"W3027161177","doi":"10.1139/cjc-2020-0016","title":"Catalytic Lewis and Brønsted acid <i>syn</i>-diastereoselective benzylic substitutions of <i>α</i>-hydroxy-<i>β</i>-nitro- and <i>α</i>-hydroxy-<i>β</i>-azido-alkyl arenes","year":2020,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthesis and Catalytic Reactions","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Nitro; Catalysis; Alkyl; Alcohol; Allylic rearrangement; Brønsted–Lowry acid–base theory; Lewis acids and bases; Organic chemistry; Stereochemistry; Medicinal chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001333512,0.0004078281,0.0002105399,0.0001139312,0.00008489333,0.000129347,0.0002778521,0.000207296,0.001246697],"category_scores_gemma":[0.000153785,0.0001335626,0.0001462631,0.0001356549,0.0001944125,0.000235438,0.0002132299,0.0003796358,0.0004656816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001900946,"about_ca_system_score_gemma":0.0002237929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005005796,"about_ca_topic_score_gemma":0.001461294,"domain_scores_codex":[0.9998688,0.00002320032,0.000008705399,0.000021284,0.00003202362,0.00004593059],"domain_scores_gemma":[0.9999371,0.000008387145,0.00002395668,0.000006867633,0.00001139004,0.00001229002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002289858,0.00004113213,0.0001365834,0.0001704554,0.00001363381,0.0001585034,0.00005826729,0.0003585042,0.9929578,0.0007220301,0.0002592273,0.004894942],"study_design_scores_gemma":[0.00002915701,0.0002962782,0.000400171,0.000005967271,0.0000110824,0.0001720494,0.00001825318,0.000480557,0.9954346,0.00007661057,0.003067441,0.000007747805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.959067,0.00228727,0.01325016,0.0002025424,0.0001229459,0.0001368159,0.0005771367,0.0002413873,0.02411486],"genre_scores_gemma":[0.9923174,0.001361077,0.003273873,0.00005989632,0.00001546059,0.00002554272,0.0002129299,0.00003689229,0.002696882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001246697,"threshold_uncertainty_score":0.004170597,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.013186121851687,"score_gpt":0.1898238868807183,"score_spread":0.1766377650290313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}