{"id":"W3027386931","doi":"10.1093/schbul/sbaa030.519","title":"M207. REVEALING HYPOTHALAMIC PATHWAYS CONTRIBUTION TO OLANZAPINE- INDUCED METABOLIC SYNDROME: FROM MURINE MODEL TO HUMAN TRANSLATION","year":2020,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Diet and metabolism studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Olanzapine; Biology; Gene; Leptin; Hypothalamus; Endocrinology; Transcriptome; Internal medicine; Schizophrenia (object-oriented programming); Gene expression; Translation (biology); Medicine; Bioinformatics; Obesity; Messenger RNA; Genetics; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003030459,0.0005359167,0.0004852923,0.0008624163,0.0003627341,0.0005362577,0.0003231963,0.0006380499,0.006573859],"category_scores_gemma":[0.0001710487,0.0003470985,0.0009347301,0.0005917349,0.0003641906,0.0002665772,0.0004523564,0.001161906,0.002249244],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003643297,"about_ca_system_score_gemma":0.0006319766,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001146288,"about_ca_topic_score_gemma":0.002253007,"domain_scores_codex":[0.9997585,0.00002830958,0.00002362567,0.00006234766,0.0000808423,0.00004635132],"domain_scores_gemma":[0.9998817,0.00001105845,0.00003394397,0.00001861996,0.00001543126,0.00003926133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001754764,0.0002626495,0.002989757,0.0007257527,0.00009661543,0.0006774963,0.00006586665,0.0003216855,0.9715078,0.0006200746,0.004312875,0.01666461],"study_design_scores_gemma":[0.001047426,0.006267728,0.07382369,0.0005144848,0.0008192109,0.006621221,0.0004466121,0.005522193,0.788931,0.001936612,0.1139748,0.00009508375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8680621,0.0158972,0.02935868,0.003477937,0.001052107,0.0006622589,0.06471652,0.003058602,0.01371455],"genre_scores_gemma":[0.8773668,0.01208043,0.03097854,0.002092663,0.0001552383,0.001614071,0.05964057,0.0005210129,0.01555067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006573859,"threshold_uncertainty_score":0.02199173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05314690575148501,"score_gpt":0.2729532681281868,"score_spread":0.2198063623767018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}