{"id":"W3027487440","doi":"10.3390/v12050579","title":"Zika Virus with Increased CpG Dinucleotide Frequencies Shows Oncolytic Activity in Glioblastoma Stem Cells","year":2020,"lang":"en","type":"article","venue":"Viruses","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; University of Saskatchewan","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; Saskatchewan Health Research Foundation","keywords":"Oncolytic virus; Glioblastoma; Zika virus; CpG site; Stem cell; Biology; Virology; Cancer research; Virus; Gene; DNA methylation; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000988965,0.0002831855,0.0005632335,0.000103341,0.00006342625,0.00005547236,0.0001674064,0.00008423503,0.0005096174],"category_scores_gemma":[0.00005529941,0.0002215981,0.0001176559,0.0003922792,0.0001007017,0.0002345021,0.00005844021,0.0002562719,0.0001678976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001264501,"about_ca_system_score_gemma":0.0003117325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001360274,"about_ca_topic_score_gemma":0.001079457,"domain_scores_codex":[0.9983742,0.00009201683,0.0002666395,0.0004652169,0.000403431,0.0003985413],"domain_scores_gemma":[0.9988688,0.0001439825,0.0001158064,0.0003582656,0.00005937205,0.0004537809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007422579,0.0006541068,0.04635758,0.0002717299,0.0001667916,0.001121203,0.0003717123,0.00007834384,0.9318975,0.0001934552,0.002066545,0.009398401],"study_design_scores_gemma":[0.009157899,0.003922141,0.06246152,0.0004423898,0.0005542829,0.00002780103,0.0008141862,0.00358601,0.9033348,0.00003185069,0.01493016,0.0007369543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973617,0.000395024,0.0001001379,0.000547918,0.00005454023,0.0006394505,0.0001351605,0.0001710033,0.000595045],"genre_scores_gemma":[0.993021,0.00003390042,0.00005892095,0.006443149,0.0002183515,0.00009931676,0.000001541858,0.00004946183,0.00007433696],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02856274,"threshold_uncertainty_score":0.9036508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02559720948917018,"score_gpt":0.2530854266845574,"score_spread":0.2274882171953872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}