{"id":"W3027487440","doi":"10.3390/v12050579","title":"Zika Virus with Increased CpG Dinucleotide Frequencies Shows Oncolytic Activity in Glioblastoma Stem Cells","year":2020,"lang":"en","type":"article","venue":"Viruses","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; University of Saskatchewan","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; Saskatchewan Health Research Foundation","keywords":"Oncolytic virus; Glioblastoma; Zika virus; CpG site; Stem cell; Biology; Virology; Cancer research; Virus; Gene; DNA methylation; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009471563,0.0001574294,0.0001598448,0.000154359,0.0000722449,0.0001867391,0.00009427948,0.0001465087,0.0007541954],"category_scores_gemma":[0.0001175792,0.00006738136,0.0001465219,0.0001224539,0.0001004918,0.0001077022,0.00009859692,0.0003240563,0.0001158223],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002341193,"about_ca_system_score_gemma":0.0001674316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003056571,"about_ca_topic_score_gemma":0.003324592,"domain_scores_codex":[0.999923,0.00001302793,0.000008074221,0.00001300091,0.00002135812,0.00002152304],"domain_scores_gemma":[0.99994,0.00001490221,0.00001372363,0.000008430015,0.0000110797,0.0000118623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004683906,0.00001715086,0.0002838643,0.000020826,0.000004654639,0.00001479272,0.00001709429,0.00005857167,0.9985371,0.00007969719,0.00001620183,0.0009033335],"study_design_scores_gemma":[0.000008923587,0.0005006766,0.003848655,0.000003068139,0.00001726509,0.00009948893,0.00002841509,0.0008161952,0.9936929,0.0000299003,0.0009520714,0.000002528046],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974065,0.0005764557,0.001179388,0.00002754094,0.000007503705,0.00002013551,0.0001702764,0.00001886656,0.0005932775],"genre_scores_gemma":[0.9969935,0.0003028392,0.001556261,0.00001747571,0.000001852338,0.00001572865,0.0003497433,0.000006351369,0.0007561499],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003056571,"threshold_uncertainty_score":0.006077588,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02559720948917018,"score_gpt":0.2530854266845574,"score_spread":0.2274882171953872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}