{"id":"W3027589761","doi":"10.1186/s12917-020-02364-w","title":"Pharmacokinetics and analgesic effects of intravenous, intramuscular or subcutaneous buprenorphine in dogs undergoing ovariohysterectomy: a randomized, prospective, masked, clinical trial","year":2020,"lang":"en","type":"article","venue":"BMC Veterinary Research","topic":"Veterinary Pharmacology and Anesthesia","field":"Veterinary","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Cegep de Saint Hyacinthe","funders":"Université de Montréal; Zoetis","keywords":"Medicine; Buprenorphine; Pharmacokinetics; Anesthesia; Carprofen; Analgesic; Morphine; Blood sampling; Propofol; Pharmacology; Opioid; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.004129805,0.0004920732,0.001730889,0.0004330036,0.0001913377,0.00008123669,0.000672541,0.0003645822,0.0002717212],"category_scores_gemma":[0.001634646,0.0004130702,0.0003328105,0.0008987782,0.001156383,0.0002356023,0.0007210663,0.001535044,0.00004915352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001067314,"about_ca_system_score_gemma":0.0004109322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001057857,"about_ca_topic_score_gemma":0.00001773281,"domain_scores_codex":[0.9895467,0.006206518,0.001482076,0.001131378,0.0006691436,0.0009641483],"domain_scores_gemma":[0.9913436,0.007314248,0.0002770574,0.0004674421,0.0001591292,0.0004385097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9365534,0.001172793,0.002356269,0.002884147,0.0003292159,0.02687654,0.001534304,0.00001835486,0.02529809,0.0001697767,0.00008987066,0.00271723],"study_design_scores_gemma":[0.8458077,0.1216843,0.01089214,0.0006945017,0.0003305401,0.009443106,0.0003372006,0.007304524,0.0006951469,0.0007588968,0.001044918,0.001006991],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927975,0.00102066,0.0003143233,0.0003770421,0.0003306138,0.004812118,0.000009882122,0.0001162556,0.0002216123],"genre_scores_gemma":[0.9957353,0.001202965,0.0018054,0.0001528227,0.0005421404,0.000351835,0.00001174949,0.00009432987,0.0001034084],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1205115,"threshold_uncertainty_score":0.9998321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2247744628145311,"score_gpt":0.4550455630621656,"score_spread":0.2302711002476346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}