{"id":"W3027738835","doi":"10.4049/jimmunol.2000156","title":"MHC-Independent Thymic Selection of CD4 and CD8 Coreceptor Negative αβ T Cells","year":2020,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Canadian Institutes of Health Research; Cancer Research Society","keywords":"CD8; Double negative; Natural killer T cell; Biology; Thymocyte; Cytotoxic T cell; T-cell receptor; CD1; T cell; Negative selection; Cell biology; Interleukin 21; Immunology; Immune system; Molecular biology; In vitro; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000139616,0.0001915507,0.0001195278,0.0002102091,0.0001041908,0.0003316468,0.0001832311,0.0001347593,0.001359408],"category_scores_gemma":[0.0001790592,0.0001060627,0.0001163832,0.00006641178,0.000110193,0.0001213558,0.0002744296,0.0003750203,0.000498827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001252042,"about_ca_system_score_gemma":0.0001481467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002405025,"about_ca_topic_score_gemma":0.0004759641,"domain_scores_codex":[0.9998385,0.00002508175,0.00001278001,0.00003381266,0.00003929762,0.00005054868],"domain_scores_gemma":[0.999768,0.00004205085,0.00004665946,0.00003033321,0.00003011108,0.00008292698],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006958703,0.000009866659,0.0009785041,0.00001184749,0.000001322252,0.0000635347,0.000009928305,0.0000199541,0.9969747,0.000127222,0.00002534332,0.001708119],"study_design_scores_gemma":[0.00003425574,0.0003505016,0.02447594,0.00002460124,0.00002264657,0.001806159,0.00008707203,0.001418009,0.9669078,0.0001952049,0.00466963,0.000008233376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935415,0.0006573151,0.002141606,0.00002596515,0.00001733938,0.00001778822,0.0001229479,0.00003850594,0.00343711],"genre_scores_gemma":[0.9953365,0.000216715,0.001073877,0.0000368752,0.000007986071,0.00001533588,0.0002694206,0.00002527996,0.003018016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001359408,"threshold_uncertainty_score":0.004547656,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.011396775939218,"score_gpt":0.2170500294944149,"score_spread":0.2056532535551969,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}