{"id":"W3027754477","doi":"10.1101/2020.05.19.104471","title":"Transient intestinal colonization by a live-attenuated oral cholera vaccine induces protective immune responses in streptomycin-treated mice","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Howard Hughes Medical Institute","keywords":"Cholera; Immune system; Cholera vaccine; Immunogenicity; Vibrio cholerae; Medicine; Immunology; Biology; Microbiology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003093365,0.0006991549,0.000432958,0.00058108,0.0001965406,0.0003991286,0.0003404936,0.0006792836,0.001993242],"category_scores_gemma":[0.000207608,0.0002419725,0.0004471366,0.0001738737,0.000524197,0.0003649149,0.0002446213,0.002101152,0.0006126626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002876275,"about_ca_system_score_gemma":0.0002601559,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003962168,"about_ca_topic_score_gemma":0.0006845222,"domain_scores_codex":[0.9995925,0.00006940348,0.0000451255,0.000113909,0.00007300269,0.0001060044],"domain_scores_gemma":[0.9995345,0.00007186239,0.0001563327,0.00006759982,0.00004463004,0.0001250583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002562785,0.000214701,0.0002295665,0.00003624974,0.000005216079,0.00003545533,0.0000333077,0.00004229686,0.9978293,0.00006023464,0.00005145189,0.001206106],"study_design_scores_gemma":[0.00008067471,0.007628978,0.005605489,0.00002488026,0.00003149241,0.0003047996,0.00008935627,0.0007903755,0.9829942,0.00006369783,0.002375711,0.00001035049],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901725,0.0008642101,0.005390954,0.0002001264,0.000086777,0.0001354725,0.0007858785,0.0002528168,0.002111366],"genre_scores_gemma":[0.9857156,0.0006748089,0.005340403,0.0002784635,0.00004257279,0.0002855465,0.001010816,0.00007404187,0.006577722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001993242,"threshold_uncertainty_score":0.006668031,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.015740556503055,"score_gpt":0.2511565911493568,"score_spread":0.2354160346463018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}